RNase H is a specific RNase that will cleave the RNA of a DNA/RNA duplex.


Carol W. Greider

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At the MRC laboratory I started the work that led to the discovery of RNase P and the enzymatic prop...
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Many molecules are known that interfere with reading, or transcribing, genes' DNA to get RNA. But no...
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Ribosomes contain RNA, messenger RNA provides the information, transfer RNAs brings the amino acids;...
CHRISTIAN DE DUVE
This last discovery illuminated the mechanism of protein synthesis: the protein chain is transferred...
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Knowing the structure of Dicer sets the stage for understanding how Dicer enzymes are involved in ot...
JENNIFER DOUDNA
Our experimental results agreed with the computational findings, indicating that these ratchetting p...
JAVIER LOPEZ
It seems likely that most if not all the genetic information in any organism is carried by nucleic a...
FRANCIS CRICK
Our experimental results agreed with the computational
findings, indicating that these ratchett...
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We found that CAS9 has the ability to make a double-stranded break in DNA at sites that are programm...
JENNIFER DOUDNA
We have only just hit the tip of the iceberg. There's a whole world of this noncoding RNA.
PETER SCHULTZ
Furthermore, neither of our research groups set out in search of RNA catalysis.
SIDNEY ALTMAN
You're showing a new part of biology that was completely unknown. Future drugs might work more effec...
CLAES WAHLESTEDT
We are sickened at the beatings and assaults on our colleagues by the RNA and police.
WARREN CHRISTOPHER
RNA interference has proven to be a quite reliable mechanism for turning genes off in a whole variet...
CRAIG MELLO
I dont think having a My Chemical Romance action figure will make a kid start his own band, I like t...
GERARD WAY
In my first publishable research, I obtained evidence that the replication of polio viral RNA engend...
J. MICHAEL BISHOP
DNA is the master blueprint for life and constitutes the genetic material in all free-living organis...
RICHARD J. ROBERTS
A DNA sequence for the genome of bacteriophage ΦX174 of approximately 5,375 nucleotides has been de...
FREDERICK SANGER
The findings may point the way to new medical interventions, such as drugs or vaccines, for infectio...
ANTHONY S. FAUCI
With this crystal structure, we've learned that Dicer serves as a molecular ruler, with a clamp at o...
JENNIFER DOUDNA
His life seemed like a deck of cards, and in the midst of all those two’s and three’s someone ha...
TEKOA MANNING
Don’t be so hard on yourself, You’re doing the same thing, trying to reconcile all the moms that...
CHRISTOPHER MOORE
You must save what you can of your life; you musn't lose it all simply because you've lost a part.
HENRY JAMES
Empathy is the new measurement of everything. It doesn't matter what religion you have, what God you...
C. JOYBELL C.
I believe that there is a Matrix and... to be more accurate I am in the Pornography Matrix.
DEYTH BANGER
I was first exposed to the idea of macro-molecular sequences while I was a postdoctoral fellow with ...
RICHARD J. ROBERTS
We can pattern a surface with single-stranded DNA containing a specific nucleotide sequence, then co...
RAVI CHANDRA
Now shall I walk or shall I ride?
'Ride,' Pleasure said;
'Walk,' Joy replied.
W.H. DAVIES
Mother Superior jump the gun...
-The Beatles, Happiness is a Warm Gun
LAUREN MYRACLE
Life is not a game. Still, in this life, we choose the games we live to play.
J.R. RIM
She wasn't bitter. She was sad, though. But it was a hopeful kind of sad. The kind of sad that just ...
STEPHEN CHBOSKY
So, I guess we are who we are for alot of reasons. And maybe we'll never know most of them. But even...
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I love my mom so much. I don't care if that's corny to say. I think on my next birthday, I'm going t...
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We Are All Infinite
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(All the grief she had suffered over her lifetime had moulded her face into a mask of eternal sadnes...
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You can't just sit there and put everyone's lives ahead of yours and think that counts as love. You ...
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I saw other people there. Old men sitting alone. Young girls with blue eye shadow and awkward jaws. ...
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That one moment when you know you are not a sad story. You are ALIVE.
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Somos quienes somos por un montón de razones.Quizás nunca conozcamos la mayoría de ellas.Pero aun...
STEPHEN CHBOSKY
Ambos dijeron que tomara asiento y parecían hablar en serio, así que me senté.
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I know these will all be stories some day, and our pictures will become old photographs. We all beco...
STEPHEN CHBOSKY
So I guess we are who we are for a lot of reasons. And maybewe'll never know most of them.
STEPHEN CHBOSKY
So I guess we are who we are for a lot of reasons. And maybe we'll never know most of them.
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There's nothing like the deep breathes after laughing that hard. Nothing in the world like a sore st...
STHEPHEN CHBOSKY
no more pencils, no more books, no more teachers' dirty looks, when the teacher rings the bell, drop...
STEPHEN CHBOSKY
I don't know the significance of this, but I find it very interesting.
STEPHEN CHBOSKY
Maybe it’s sad that these are now memories. And maybe it’s not sad.
STEPHEN CHBOSKY
During normal cell metabolism, RNA is constantly being made and broken down. The purine and pyrimidi...
RICHARD J. ROBERTS
Life is a re-discovery.
BRIAN BLESSED
If you think that life is a celebration full of party poppers and merry go rounds it's not it's a ga...
GARY F EVANS...
Life Is a Misconception.
DEYTH BANGER
Life is a desire!
DEYTH BANGER
To trust someone you must firstly remember that it is a two way street that will go all the way if y...
GARY F EVANS...
It is a lie.
ARTHUR MILLER
A man by his sin may waste himself, which is to waste that which on earth is most like God. This is ...
A.W. TOZER
She was scarcely a year older than I was, dark-haired, slender, with a face that would break your he...
GEORGE R.R. MARTIN
What we were able to do is compare the binding site of both the viral RNA and the cells' cap binding...
EVA NOGALES
I love thee for a heart that’s kind--not for the knowledge in thy mind.
W.H. DAVIES
The striking evolutionary conservation of ratchetting points suggests that recursive splicing provid...
JAVIER LOPEZ
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I'm fucking the grave, I thought, I'm bringing the dead back to life...
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I was very grateful to have heard it again. Because I guess we all forget sometimes. And I think eve...
STEPHEN CHBOSKY
I guess we are who we are for a lot of reasons. And maybe we'll never know most of them. But even if...
STEPHEN CHBOSKY
Well, you can't know it without something having been sneezed.
A.A. MILNE
We'll be Friends Forever, won't we, Pooh?' asked Piglet.
Even longer,' Pooh answered.”
...
A.A. MILNE
For me, my life is a journey.
JAY ELECTRONICA
I am often asked how it is that I am able to value people to such a deep degree. Apparently, I exhib...
C. JOYBELL C.
I read as much poetry as time allows and circumstance dictates: No heartache can pass without a litt...
J. COURTNEY SULLIVAN
Love isn't the work of the tender and the gentle;
Love is the work of wrestlers.
The one w...
JALALUDDIN MEVLANA RUMI
The opportunity to decieve others is ever present and often tempting, and each instance of deception...
SAM HARRIS
Life is a risk.
CARMELO ANTHONY
This is such a very different type of DNA testing than people know about. It's very different from f...
HENRY YENNIE
What I found out on Christmas Day 1984, through biochemical evidence, was that telomeres could be le...
CAROL W. GREIDER
Federal funding for biomedical sciences plays a critical role in training the next generation of sci...
CAROL W. GREIDER
I enjoyed biology in high school, and that brought me to a research lab at U.C. Santa Barbara. I lov...
CAROL W. GREIDER
In junior high school, I learned that I could be good at school. I remember liking the freedom to ch...
CAROL W. GREIDER
My father worked in high-energy nuclear physics, and my mother was a mycologist and a geneticist. Af...
CAROL W. GREIDER
In 1978, Elizabeth Blackburn, working with Joe Gall, identified the DNA sequence of telomeres. Every...
CAROL W. GREIDER
What intrigues basic scientists like me is that anytime we do a series of experiments, there are goi...
CAROL W. GREIDER
As a kid, I thought of myself as stupid because I needed remedial help. It was not until much later ...
CAROL W. GREIDER
Students and postdoctoral fellows largely depend on the support of the public sector to finance the ...
CAROL W. GREIDER
I finished my Ph.D. at Berkeley in November 1987 and took a position as an independent fellow at Col...
CAROL W. GREIDER
I think actively promoting women in science is very important because the data has certainly shown t...
CAROL W. GREIDER
Science can promote an understanding between people at a really fundamental level.
CAROL W. GREIDER
One of the lessons I have learned in the different stages of my career is that science is not done a...
CAROL W. GREIDER
Be grateful for every moment and every breath.
TERESA COLLINS
Without music, life is a journey through a desert.
PAT CONROY
Life is a journey. When we stop, things don't go right.
POPE FRANCIS
The striking evolutionary conservation of ratchetting points
suggests that recursive splicing p...
JAVIER LOPEZ
I wish I was home", She said miserably.
She tried so hard to be brave,
to be fierce as a...
GEORGE R.R. MARTIN
No time to see, in broad daylight,
Streams full of stars, like skies at night.

No ti...
W.H. DAVIES
This man has talent, that man genius
And here's the strange and cruel difference:
Talent g...
W.H. DAVIES
I'm not saying that I'm better than anyone... I'm just saying that I'm one-of-a-kind.
C LIONG
A person of value have skill, a vision & a deep desire to achieve what they dream for. Happiness com...
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A man of guilt acknowledges and changes himself immediately on being hinted slightly about his fault...
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The school year progressed slowly. I felt as if I had been in the sixth grade for years, yet it was ...
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The value of a consultant;An outsider can see what an insider cannot see or has decided to ignore.
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A family is like a card game, on one hand, you can get a really bad hand and on the other, your hand...
GARY F EVANS...
The worth of a person’s quote is in his or her heart where it takes the birth and the value of the...
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Walking the rugged trail of the unknown destiny can be filled with walls crashing and cracks on the ...
GARY F EVANS...

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When you have a dream, you've got to grab it and never let go.
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I never drank except a couple sips of wine at Thanksgiving.
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Comedy is tragedy - plus time.
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We all get where we're going by circuitous journeys, and some of the setbacks are warranted.
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You have to go through the falling down in order to learn to walk. It helps to know that you can sur...
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When things are a disappointment, try not to be so discouraged.
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When I get tired, I start eating things that I wouldn't normally crave, like biscuits, because t...
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I struggled for a while, but when I was cast in an Off Broadway show called 'Once Upon a Mattres...
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The photoshoot glitz and TV studio make-up isn't the real me. I spend most days at home in Brist...
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But I didn't ask to have somebody nose around in my private life. I didn't even ask to be fa...
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I had a good loud voice and I wasn't afraid to be goofy or zany.
CAROL BURNETT
I very much enjoyed doing 'Law & Order,' playing a killer - that was fun, and they had a...
CAROL BURNETT
I do the 'New York Times' crossword puzzle every morning to keep the old grey matter ticking...
CAROL BURNETT
I've always been able to recount things, and I have a really good memory about dialog and what p...
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Funny is funny. I dare anyone to look at Tim Conway and Harvey Korman doing the dentist sketch, whic...
CAROL BURNETT
I think the hardest thing to do in the world, show-business-wise, is write comedy.
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On the good days, my mother would haul out the ukulele and we'd sit around the kitchen table - i...
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Because nobody goes through life without a scar.
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Just scream! You vent, and the body just feels good after a good old yell.
CAROL BURNETT
I'm so happy with what has happened in my life.
CAROL BURNETT
I liked myself better when I wasn't me.
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It is the instinctive wish of most American businesspeople, even those unlikely to be directly affec...
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When they are employed wisely, derivatives make the world simpler because they give their buyers an ...
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. . . while men represent powerful activity as assertion and aggression, women in contrast portray...
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I can't be bothered to go to the gym, though. I honestly just can't be bothered - it's t...
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In the 1987 stock market crash, according to the conclusions of the official Brady report, colossal ...
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I was a very lonely child and it's funy but the first word that comes to my head is "starved". I fel...
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I think we're here for each other.
CAROL BURNETT
Only I can change my life. No one can do it for me.
CAROL BURNETT
Get out of the blocks, run your race, stay relaxed. If you run your race, you'll win. Channel your e...
CAROL LEWIS
I'm not into working out. My philosophy: No pain, no pain.
CAROL LEIFER
Comedy is a tragedy plus time.
CAROL BURNETT
Abortion is a skillfully marketed product sold to women at a crisis time in their life. If the produ...
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...As in all moral panics, an accusation is enough to destroy a person's life. Hysteria trumps evi...
CAROL TAVRIS
The real problem between the sexes is that for men, sex is a gender-underliner, they need it for the...
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Giving birth is like taking your lower lip and forcing it over your head.
CAROL BURNETT
The product, abortion, is skillfully marketed and sold to the woman at the crisis time in her life. ...
CAROL EVERETT
There is no old age. There is, as there always was, just you.
CAROL MATTHAU
In 1980, aided by $1.5 billion in loan guarantees from the U.S. government and his own pitchman rout...
CAROL LOOMIS
In the different voice of women lies the truth of an ethic of care, the tie between relationship and...
CAROL GILLIGAN
New legislation has just been adopted by the International Labour Organization on the Worst Forms of...
CAROL BELLAMY
I would love to have written Roger Zelazny's first five books of 'Amber.' What a great i...
CAROL BERG
And my first film was Carnal Knowledge, another amazing experience, largely because of Mike Nichols,...
CAROL KANE
Limited partnerships are required to amend their filings whenever important changes, such as the adm...
CAROL LOOMIS
When I was in college at UCLA, I took a playwriting course. I was all set to be a writer. But I had ...
CAROL BURNETT
Some managements do not even think of buybacks as an option. The idea of shrinking their equity base...
CAROL LOOMIS
Adolescence is just one big walking pimple.
CAROL BURNETT
It's also selfish because it makes you feel good when you help others. I've been helped by a...
CAROL BURNETT
There are chapters in every life which are seldom read and certainly not aloud.
CAROL SHIELDS
When I'm photographing, I think - like any rescue worker who deals with tragedy - you have to ha...
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I find the question of whether gender differences are biologically determined or socially constructe...
CAROL GILLIGAN
I don't have false teeth. Do you think I'd buy teeth like these?
CAROL BURNETT
Everybody I know who is funny, it's in them. You can teach timing, or some people are able to te...
CAROL BURNETT
We don't stop going to school when we graduate.
CAROL BURNETT
I'm glad I was born when I was. My time was the golden age of variety. If I were starting out ag...
CAROL BURNETT
Those with dissociative disorders face a big enough battle living as multiples and dealing with past...
CAROL BROAD
There needs to be a nationwide awareness programme for all NHS staff, to educate them about dissocia...
CAROL BROAD
... in some sense, she ignored her physical self, as if her body were merely something impersonal ve...
CAROL LEE
My parents never recognized the things that for me were achievements. I was praised for the things t...
CAROL LEE
I was diagnosed with hypoglycemia, an abnormal decrease of sugar in the blood. Eventually I learned ...
CAROL ALT
If I'm making a movie and get hungry, I call time-out and eat some crackers.
CAROL ALT
I don't eat celery. I eat raw milk, cheeses.
CAROL ALT
We must ensure that while eliminating child labor in the export industry, we are also eliminating th...
CAROL BELLAMY
I suddenly had this really mad desire to have an affair with a woman. I was divorced. I was childles...
CAROL LEIFER
But what attracted me to weeds was not their beauty, but their resilience. I mean, despite being so ...
CAROL VORVAIN
More than 55,000 men from Bomber Command lost their lives, of whom 38,000 were British. That's o...
CAROL VORDERMAN
Well, I don't know how astute I am, but I did want to be a journalist when I was growing up.
CAROL BURNETT
Just be your authentic self because there's nothing sexier or more beautiful than that.
CAROL LEIFER
It's not about failure; it's about trying something and risking something for attaining your...
CAROL ALT
The speed and trajectory of BlackRock's ascent have been breathtaking.
CAROL LOOMIS
My grandmother and I followed my mother here, to a house a block north of Hollywood Boulevard but a ...
CAROL BURNETT
My grandmother and I would go see movies, and we'd come back to the apartment - we had a one-roo...
CAROL BURNETT
I enjoy worldbuilding very much. I generally start with an approximation. With 'Flesh and Spirit...
CAROL BERG
Laughter is much more important than applause. Applause is almost a duty. Laughter is a reward.
CAROL CHANNING
I had gone to nursing school at Northampton Community College in my hometown of Bethlehem, Pennsylva...
CAROL GUZY
I have a whole box full of pieces of the Berlin Wall and a heart made from the barbed wire of the Ir...
CAROL GUZY
She suffered. She suffered a whole lot. And at one point I was praying for her to be released. You k...
CAROL BURNETT
When you have a dream you've got to grab it and never let go
CAROL BURNETT
She was a mountain girl, ... We brought some of her ashes here and placed them next to F.C. Jones. I...
CAROL BURNETT
People invite me to dinner not because I cook, but because I like to clean up. I get immediate grati...
CAROL BURNETT
I don't have false teeth. Do you think I'd buy teeth like these?
CAROL BURNETT
Giving birth is like taking your lower lip and forcing it over your head.
CAROL BURNETT
She said, 'Mama, if I can take it back ...,
CAROL BURNETT
I have always grown from my problems and challenges, from the things that don't work out, that's whe...
CAROL BURNETT
I do think there are some great female comics: Tina Fey, Amy Poehler, Kristen Wiig, Maya Rudolph. Th...
CAROL BURNETT
I'm not always optimistic. You wouldn't have all cylinders cooking if you were always like M...
CAROL BURNETT
I'm hooked on Glenn Close in 'Damages.'
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The good thing about a dealer's derivatives portfolio is that it is marked to market.
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I believe in lieu of the Katrina situation last week it is even more important that we are prepared ...
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The faculty will be a little more relaxed this semester, because we know that problems are inevitabl...
CAROL MILLER
I came in Tuesday and took a tour of the building for the first time. My first impression was that E...
CAROL MILLER
Many people have been able to return to their homes. We expect to spend most of today assessing dama...
CAROL MILLER
People have really improved their recycling efforts.
CAROL MILLER
It was very moving and extremely needed, ... We are a conservative campus where this is not talked a...
CAROL MILLER
The goal is to have at least one quarter of the amount of trash that would have gone to the landfill...
CAROL MILLER
So far this year we have taken in 108.5 tons of recyclable versus the estimated 65.6 tons collected ...
CAROL MILLER
The students were definitely the first priority, that's why they have finished all the classrooms. T...
CAROL MILLER
We could always use more, but we are getting back on schedule after the holiday.
CAROL MILLER
Say you get to some place and you can't find an ATM. I will only get one or two or three days worth ...
CAROL MICKELSEN
Europe is very close to what you would find in the U.S. If you're going to a very small town in Amer...
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[Europe is closest to North America in its density of ATMs.] ATM machines are all over the place. Th...
CAROL MICKELSEN
In Poland, we could pay for groceries with a credit card. Surprisingly enough, campgrounds take char...
CAROL MICKELSEN
In Poland, we could pay for groceries with a credit card, ... Surprisingly enough, campgrounds take ...
CAROL MICKELSEN
Say you get to some place and you can't find an ATM, ... I will only get one or two or three days wo...
CAROL MICKELSEN
Response times will be better.
CAROL MEYER
You as a resident need to make yourself prepared and knowledgeable.
CAROL MEYER
I'd say we're probably one of the most prepared counties in the country.
CAROL MEYER
It's awesome. I thought it would be a wonderful opportunity. I very much favor the Philharmonic.
CAROL MEYER
Trauma funds aren't going into the San Gabriel Valley, but paying for the trauma patients that get t...
CAROL MEYER
We both do all the work, but we each have the places where we shine.
CAROL MCNEELY
We think every home needs at least one, or maybe two or three, decorative rooms.
CAROL MCNEELY
We tailor finishes to people's personalities.
CAROL MCNEELY
We want people to know that we do more than stripes and polka dots.
CAROL MCNEELY
She was a feisty woman. She was a clown. She made everyone laugh. Everyone loved to be around her.
CAROL MARSH
It all happened very fast. In 10 minutes, the whole thing was gone.
CAROL MARSH
This is how close we were.
CAROL MARSH
My grandmother was a feisty woman. That's probably the best way to describe her. She was still deliv...
CAROL MARSH
Our guests, when they arrive on board, they are going to see that. When they depart, they are going ...
CAROL MARLOW
The response has been remarkable.
CAROL MARLOW
We spent longer than we had planned in Fort Lauderdale, which meant that the itinerary has had to be...
CAROL MARLOW
Cunard has the unique distinction of having the only true liners in the industry, and we're proud to...
CAROL MARLOW
We gave our guests a compensation package which we felt was fair, and clearly it's not our intention...
CAROL MARLOW
Queen Victoria will be a classically-styled Cunard queen, offering the very best of our heritage, al...
CAROL MARLOW
The arc of your swing doesn't have a thing to do with the size of your heart.
CAROL MANN
Her swing changed in a way I hadn't seen before. She quit turning and got steep. She stopped being a...
CAROL MANN
The Open is the home of the over-try.
CAROL MANN
Before mental skills can really make a difference, a golfer has to develop swing skills and course m...
CAROL MANN
[Cherry Hills will be used as support for the argument that Wie's path will leave her not only with ...
CAROL MANN
What happens is that women tend to panic when they're losing it. Whereas, generally speaking, men, r...
CAROL MANN
It pretty much becomes an off-leash day every day. That's what's happening now again.
CAROL MAJESKE
If they don't follow the rules there may not be any choice in the future but to do further restricti...
CAROL MAJESKE
Those who choose not to follow the rules may ruin it for the dog owners that are complying.
CAROL MAJESKE
It's just a stressful situation for wildlife who are already stressed out in the winter.
CAROL MAJESKE
That's the age when classes start to become departmentalized and this could be the first manifestati...
CAROL LOEWITH
The problem with these classes is that the tutoring is usually done in small groups rather than one-...
CAROL LOEWITH
Before you run off to a million different tutoring systems, have the school test the student to see ...
CAROL LOEWITH
Before you usher them off to a tutoring center it would really pay for the parent to talk to the tea...
CAROL LOEWITH
What you're doing is, you're paying $22.8 million for the privilege of putting up $100 million. At t...
CAROL LICKO
Scripps is not being difficult in this. We've tried every which way to come to agreement with the co...
CAROL LICKO
[Scripps] would have never bet its institute on this. They didn't do it on Mecca, and they're certai...
CAROL LICKO
Scripps is a science institute. We don't want to be suing the county.
CAROL LICKO
The party here that is trying to renege on their agreement is the county. Where's its obligation to ...
CAROL LICKO
He had all these tricks he used. He's not a dumb person, by any means. He just didn't get it in scho...
CAROL LEWIS
People really seem to like the larger facility.
CAROL LEWIS
Near the end of the year, we always run short.
CAROL LEWIS
The community is generous, but with all the bills going up, it?s getting expensive to run.
CAROL LEWIS
We have not behaved well as a board of education. It is a disgrace and a shame. We need to rectify t...
CAROL LEWIS
What these people say is true. It's really unfortunate.
CAROL LEWIS
This spin control stuff is not working when people are dying, ... You want to be supportive of the c...
CAROL LEWIS
They should have had acts that the young people can identify with. I'm not even feeling it. Maybe my...
CAROL LEWIS
I don't have the manpower to go out and check to see if people are smoking. We had to cut down on la...
CAROL LEWIS
Throughout history, when our national security has been threatened, we have responded by reducing li...
CAROL LEWIS
We'll give it a good shot. We could do well or we could get killed.
CAROL LEVINE
I've been teaching tennis for 25 years.
CAROL LEVINE
You make a lot of adjustments in the early years, and it gets easier.
CAROL LEVINE
It is a safe assumption,
CAROL LEVINE
Because men who do any significant kind of caregiving are often seen by family and friends as heroic...
CAROL LEVINE
Being thrust into the role of caregiver without any preparation is difficult under any circumstances...
CAROL LEVINE
They are not seen as doing anything but helping out, as kids are supposed to do.
CAROL LEVINE
This is a tremendous sense of guilt and burden that children should not have to bear.
CAROL LEVINE
We had no jobs, no place to live. At his first job he worked for $400 a month.
CAROL LEVINE
This does not have the earmarks of a long-planned management transition.
CAROL LEVENSON
Getting into a bidding war with J&J is bad enough. But getting into a cash-throwing contest with J&J...
CAROL LEVENSON