Magnesium’s role in bone health is multifaceted. • Adequate levels of magnesium are essential for the absorption and metabolism of calcium. • Magnesium stimulates a particular hormone, calcitonin, that helps to preserve bone structure and draws calcium out of the blood and soft tissues back into the bones, preventing some forms of arthritis and kidney stones. • Magnesium suppresses another bone hormone called parathyroid, preventing it from breaking down bone. • Magnesium converts vitamin D into its active form so that it can help calcium absorption. • Magnesium is required to activate an enzyme that is necessary to form new bone. • Magnesium regulates active calcium transport. With all these roles for magnesium to play, it is no wonder that even a mild deficiency can be a risk factor for osteoporosis. Further, if there is too much calcium in the body, especially from calcium supplementation, as in Muriel’s case, magnesium absorption can be greatly impaired, resulting in worsening osteoporosis and the likelihood of kidney stones, arthritis, and heart disease. A chance meeting in a hotel with a woman whose lymphoma worsened immediately after being prescribed 2,500 mg of calcium, but no magnesium, for her osteoporosis made me consider that excess calcium can also deposit in cancerous tumors. Other factors that are important in the development of osteoporosis include diet, drugs, endocrine imbalance, allergies, vitamin D deficiency, and lack of exercise. A detailed review of the osteoporosis literature shows that chronically low intake of magnesium, vitamin D, boron, and vitamins K, B12, B6, and folic acid leads to osteoporosis.

Carolyn Dean