A fundamental premise in cancer therapy is trying to identify how the metabolism of cancer cells differs from normal tissue. When differences are identified, it often paves the way for treatments that will disrupt the cancer's metabolism while sparing normal tissue.
David Perlmutter
Related One of the longstanding problems in medicine is how to cure cancer without harming normal body tissu... HONGJIE DAI The drugs that are being developed are being developed to target specific protein or enzyme systems ... DAVID GREENWALD Under normal circumstances, testosterone is what stimulates prostate cancer to grow, so one form of ... PAUL BARRETT So many cancer therapies are as poisonous to healthy cells as they are to cancer cells. A therapy th... CRAIG MEYERS Since cancer is an anaerobic growth, enhancing aerobic metabolism in a cancer patient is like shinin... PATRICK QUILLIN Breast cancer is thought to use cholesterol to help the cancer migrate and invade more tissue. MICHAEL GREGER When are we going to say cancer is cured? I'm not sure when that will happen, if that will happe... DAVID BALTIMORE I was working with stem cells as part of a NASA programme. We realised that the science of stem-cell... PATRICK SOON-SHIONG You can never be assured of removing all breast tissue. But it is a huge reduction in breast cancer. EMILY HARRIS I had male breast cancer and had dual radical modified mastectomy, and I've spent a lot of time ... EDWARD BROOKE [ERBITUX targets metastatic colorectal cancer cells expressing epidermal growth factor receptors (EG... BARRY STEIN She went from living this normal life to living a cancer life. JULIE SCHERF At the highest concentration of ascorbic acid, if given intravenously, they don't touch normal cells... MARK LEVINE It turns out that the very genes that turn on in cancer cells perform vital functions in normal cell... SIDDHARTHA MUKHERJEE Measuring prognostic markers in breast cancer cells opens up possibilities for broad applications of... DR. RAFAEL NUNEZ For prostate cancer, if you look around the world, there might be 50-fold or greater differences in ... MEIER STAMPFER In time, targeted gene therapy may help improve the outlook for many types of cancer. While we have ... JACK ROTH Think about breast cancer. It can take seven years for breast cells to go from pre-cancerous to canc... DR. CAROLYN RUNOWICZ The model using the PC3 prostate cancer cells is irrelevant. So, the implications of the findings to... AJIT K. VERMA When you have cancer, it's like you enter a new time zone: the Cancer Zone. Everything in the Tr... REGINA BRETT Some humans are like the cancer cells for the planet earth! PRATIK SHARDA We can show that there are differences in the profiles of chemicals that come from the tissue, and t... JUSTIN WISEMAN Every cancer looks different. Every cancer has similarities to other cancers. And we're trying t... HAROLD E. VARMUS In retrospect, I have devoted my scientific life mainly to the question to what extent infectious ag... HARALD ZUR HAUSEN It's therapy. That's what it is, it's therapy. I am living with cancer, but I'm not going to die of ... GEORGE DACY There is no accepted early screening technique for lung cancer. The PLCO trial will show if chest X-... CHRISTINE BERG We know cancer is caused ultimately via a link between the environment and genes. There are genes in... SIDDHARTHA MUKHERJEE The most dangerous cancer cells are actually the ones that are more like stem cells, which have this... ELIZABETH BLACKBURN Cancer is cancer. When it touches you, you think about every type of cancer, every illness that's ou... KANDACE OLNEY There are some exciting new molecular-targeted drugs that are helpful, and we're understanding the m... JAY BROOKS Dr. Alt's discoveries have led to a greater understanding of the ways that cancers of immune cells d... MARSHALL LICHTMAN The National Cancer Institute wants to make certain the results of clinical research are rapidly dis... ANDREW VON ESCHENBACH In the laboratory, our researchers have been very impressed with the ability of these extracts to sl... AARON KATZ It will be in the convergence of evolutionary biology, developmental biology and cancer biology that... PAUL DAVIES Where does my body end and an invader start? And cancer, a tumor, is something you grow out of your ... DAVE DEBRONKART Cancer essentially lives in us and becomes activated at some point, and then cells begin to psychoti... EVE ENSLER Cancer is a disease of the genome. And that's what happens. You make mistakes in a cell somewher... FRANCIS COLLINS The fact that cancer remains the leading cause of death by disease in children makes me so committed... ERIC GREENBERG Antioxidants are chemicals that break down or neutralize the damaging effects of free radicals - che... DAVID PERLMUTTER FTIs, originally developed for cancer, are capable of reversing the dramatic nuclear structure abnor... FRANCIS COLLINS The model using the PC3 prostate cancer cells is irrelevant. So the implications of the findings to ... AJIT K. VERMA The Federal government has not committed sufficient resources to researching how the disease starts ... REGINA VIDAVER Broccoli is incredible. It can prevent DNA damage and metastatic cancer spread; activate defences ag... MICHAEL GREGER You can be a victim of cancer, or a survivor of cancer. It's a mindset. DAVE PELZER [PBO is classified as a carcinogen,] but it's not truly one in its own right, ... It inhibits the me... ARTHUR CRAIGMILL This is sham therapy. It has absolutely no effect on cancer cells. And tragically, some consumers lo... HOWARD BEALES The biggest issue with lung cancer, as we know, is that smoking is the number one cause of lung canc... KAREN CARPENTER The scientific evidence is substantial and it indicates that hormone replacement therapy causes brea... HOWARD SNYDER Relay For Life is as much an awareness raiser about the progress against cancer as it is a fundraise... LINDA RICHEY These proposals represent a bold reform package for the future but they don't solve the problem of t... JOANNE WHALLEY A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reo... SIDDHARTHA MUKHERJEE What we want is not just that they construct a building but that they also build the community. The ... EMILIO HERNANDEZ It's unconscionable that cancer patients get the wrong diagnosis 30 percent of the time and that... PATRICK SOON-SHIONG We believe that AAV-2 recognizes that the cancer cells are abnormal and destroys them. This suggests... CRAIG MEYERS Epigenetics doesn't change the genetic code, it changes how that's read. Perfectly normal ge... BRUCE LIPTON 'Early stages' is when the cancer is completely contained within the prostate. If it is dete... LEN DAWSON Our study, while early, adds to growing evidence that pomegranates contain very powerful age... HASAN MUKHTAR There is a duality in recognising what an incredible disease it is - in terms of its origin, that it... SIDDHARTHA MUKHERJEE If you have cancer of the stomach, doctors would go in with the instrument and remove that area of t... WILLIAM PEINE You don't want to inhibit cell division. You want to inhibit cell division in the cancer cells, ... TIM HUNT This is a first step in showing that we can restore a normal, functioning gene in a cancer cell, a g... JACK ROTH One of the potential uses we envision is to use the ART treatment as a way to use tumor components t... DAVID MCKEAN One of the potential uses we envision is to use the ART treatment as a way to use tumor components t... DAVID MCKEAN The flip side of suicide is that it leaves a lingering question in the minds of the people who survi... ABRAHAM VERGHESE What you are exposed to during breast development may be particularly important in determining futur... JULIE KNIGHT Montana's cancer issues are different from cancer issues in New York. That's why each state needs it... DR. EDDIE REED If certain bacteria, fungi, or algae inch across something made of copper, they absorb copper atoms,... SAM KEAN Exactly 100 years after Einstein first explained this effect, we have found a way to make it useful ... GELSOMINA DE STASIO Tobacco smoke contains chemicals that weaken the body's immune system, making it more susceptibl... MICHAEL GREGER We observed quite striking differences. This suggests there are racial and ethnic differences in the... CHRISTOPHER HAIMAN There is only one things in this world shittier than biting it from cancer when you're sixteen, and ... JOHN GREEN I had to drive myself, and radiation makes you very tired. This is a Godsend for cancer treatments. ROGER LANDRY Colorectal cancer is the third leading cause of cancer in women, and it's the third leading cause of... DR. CHAD POTTEIGER Targeted cancer therapies, therapies that exploit the particular weaknesses of different types of ca... DR. RAFAEL NUNEZ Our goals were to address the following, ... Does ascorbate in pharmacologic concentrations kill can... MARK LEVINE Although awareness of cancer's prevalence in the United States improves and medical advances in ... CHRIS VAN HOLLEN Our study shows that we need to re-evaluate the effect of protons on biological systems, even the ef... BETSY SUTHERLAND It is also able to make prostate cancer cells undergo apoptosis -- programmed cell death -- and the ... HASAN MUKHTAR It is also able to make prostate cancer cells undergo apoptosis -- programmed cell death -- and the ... HASAN MUKHTAR When you die, it does not mean that you lose to cancer. You beat cancer by how you live, why you liv... STUART SCOTT In cancer we're talking about understanding the process by which these cells malfunction, and hopefu... DR. GENEROSA GRANA Don't tell me you're one of those people who becomes their disease. I know so many people like that.... JOHN GREEN We found that the proliferation rates in certain types of cancer cells was inhibited by 80 percent. BIN YE We estimate that 90,000 deaths due to cancer could be prevented each year in the United States if me... MICHAEL THUN Cancer cells come pre-programmed to execute a well-defined cascade of changes, seemingly designed to... PAUL DAVIES We talk about cancer as a noun, as if it's a one time event: 'I've got cancer.' DAVID AGUS When he had cancer, we both stopped talking to God for a while. BONNIE SHUMAN I'm taking special treatments for the cancer in my brain and in my liver. Part of the liver was ... JIMMY CARTER I recently formed a foundation to raise awareness for prostate cancer. I feel it's very necessar... HERBIE MANN Like we handle antibodies against foreign proteins and we only get viruses like measles and chicken ... DAVID GREENWALD It's a scary word, 'cancer.' ALAN JACKSON All seven groups concluded that the decline in the rate of death from breast cancer is a combination... DONALD BERRY Today's approval is a major step forward in making breakthrough treatments available for patients wi... DR. STEVEN GALSON The concept of the tripartite nexus also gives us insight into how to develop novel drugs to save ce... DOUGLAS GREEN My father died of brain cancer in 1991. I do not know anyone whose life has not been touched by the ... ALICIA COPPOLA We applaud the B.C. government for its leadership in this important and emerging area of cancer prev... BARBARA KAMINSKY C.J.'s cancer is really hard to tell how long it will take. It could be today or a year from now. We... DEBBIE BAKER The issue I will highlight is the chemicals in cigarette smoking that can lead to the changes in the... ALAN LAU Once you've had cancer, you're more likely to get secondary cancers because of the treatments, and I... LISA ROGERS Cancer is a disease that touches many lives, and the proceeds from the luncheon will provide an exce... BARBARA BUSH
More David Perlmutter
Dementia is our most-feared illness, more than heart disease or cancer. DAVID PERLMUTTER Our ancestors relied upon their advanced brains to survive during times of food shortage, and fortun... DAVID PERLMUTTER Saturated fat is a fundamental building block for brain cells. It's certainly interesting to con... DAVID PERLMUTTER Throughout our lifetimes, we are constantly regenerating new brain cells in the hippocampus, a proce... DAVID PERLMUTTER Bad things happen. And the human brain is especially adept at making sure that we keep track of thes... DAVID PERLMUTTER Rarely, Type 2 diabetes develops without any readily identifiable predisposing factor. But in the gr... DAVID PERLMUTTER Two forms of fat that are vitally important for brain health are cholesterol and saturated fat. DAVID PERLMUTTER Strokes are categorized as either bleeding into the brain or a blockage in blood supply, known as an... 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DAVID BAILEY I hate being so nostalgic about the Sixties. DAVID BAILEY People want security in this insecure world. DAVID BAILEY I don't think my work does reflect my nationality - I don't like the idea of nationalism. DAVID BAILEY It's not about composition. It's the way you feel about how your objects should relate to ea... DAVID BAILEY Girls are more attractive to me than dresses. DAVID BAILEY Rockers are the nicest people to photograph. They have no inhibitions. DAVID BAILEY Being trendy is dangerous. I've never been trendy, which is why I've never really fallen out... DAVID BAILEY I don't see the point of photographing trees or rocks because they're there and anyone can p... DAVID BAILEY If you're curious, London's an amazing place. DAVID BAILEY I was surrounded by strong women so it had never even occurred to me that women were anything other ... DAVID BAILEY The skull is nature's sculpture. DAVID BAILEY Anybody can be a great photographer if they zoom in enough on what they love. DAVID BAILEY Being handsome wasn't much of a burden. It worked for me. DAVID BAILEY Everything I read about hitting a midlife crisis was true. I had such a struggle letting go of youth... DAVID BOWIE I had a wonderful childhood, which is tough because it's hard to adjust to a miserable adulthood... LARRY DAVID You would think that a rock star being married to a supermodel would be one of the greatest things i... DAVID BOWIE People use irony as a defense mechanism. DAVID BYRNE Sometimes it's a form of love just to talk to somebody that you have nothing in common with and ... DAVID BYRNE I certainly agree that putting everything into little genres is counterproductive. You're not go... DAVID BYRNE Analysis is like a lobotomy. Who wants to have all their edges shaved off? DAVID BYRNE I knew I wanted to have a doll of myself on the cover. I thought, I wanna see myself as a Ken doll. DAVID BYRNE I've been in beautiful landscapes where one is tempted to whip out a camera and take a picture. ... DAVID BYRNE That's the thing about pictures: they seduce you. DAVID BYRNE Deep down, I know I have this intuition or instinct that a lot of creative people have, that their d... DAVID BYRNE If anything, a lot of electronic music is music that no one listens to at home, hardly. It's rea... DAVID BYRNE My favorite time of day is to get up and eat leftovers from dinner, especially spicy food. DAVID BYRNE On a bike, being just slightly above pedestrian and car eye level, one gets a perfect view of the go... DAVID BYRNE I never listen to the radio unless I rent a car. DAVID BYRNE The arts don't exist in isolation. DAVID BYRNE There's a certain amount of freedom involved in cycling: you're self-propelled and decide ex... DAVID BYRNE Real beauty knocks you a little bit off kilter. DAVID BYRNE Do I wear a helmet? Ugh. I do when I'm riding through a precarious part of town, meaning Midtown... DAVID BYRNE Cycling is a joy and faster than many other modes of transport, depending on the time of day. It cle... DAVID BYRNE You can know or not know how a car runs and still enjoy riding in a car. DAVID BYRNE You create a community with music, not just at concerts but by talking about it with your friends. DAVID BYRNE Cycling can be lonely, but in a good way. It gives you a moment to breathe and think, and get away f... DAVID BYRNE Everything's intentional. It's just filling in the dots. DAVID BYRNE I like time off. I'm not a workaholic. DAVID THEWLIS I've had an awful lot of good fortune. DAVID CASSIDY Every day is a blessing - not to get too schmaltzy, but, really, it is. DAVID CASSIDY What happened to me during the last couple of years of 'The Partridge Family' was I became s... DAVID CASSIDY There were times when I was a joke, but talent survives. DAVID CASSIDY You can't be 24 again; you can't be new when you're 40 years old. DAVID CASSIDY Most people view success by the results, and I don't. DAVID CASSIDY I think of my career as something apart from myself. DAVID CASSIDY You know, many people who become famous and enjoy great success when they're young disappear aft... DAVID CASSIDY I wouldn't want to play anything bigger than 10,000 again. I think it's too much, and you lo... DAVID CASSIDY Let me tell you, 10,000 is an intimate room. Believe me. I want to be able to connect to everybody i... DAVID CASSIDY When you cut your life into a film - 90-some minutes of film - you end up taking snapshots and vigne... DAVID CASSIDY Until I really dealt with a lot of the demons in my life - the fear and self-doubt and unresolved is... DAVID CASSIDY I gave up my whole life to my career. DAVID CASSIDY Just getting your name in the papers and having people talk about you is not always a good thing. DAVID CASSIDY There's nothing wrong with becoming a role model, nothing wrong with inspiring people to become ... DAVID CASSIDY It's always nice to have people love you, but I'd just like to be judged fairly. DAVID CASSIDY It wasn't until later when people became aware of my writing that I would hear begrudgingly, ... DAVID CASSIDY If people respond to the songs, whether they love you or hate you, then you've really done your ... DAVID CASSIDY Anybody who carries the albatross of that teen-idol thing - well, people tend to look and say: '... DAVID CASSIDY I don't want to end up being some joke on a bad TV series. DAVID CASSIDY I just want to continue to produce good work. I don't want to do junk. DAVID CASSIDY Just do me a favor. Don't call me 'former teen heartthrob,' okay? It's as if they we... DAVID CASSIDY I hitched up to Haight-Ashbury in the Summer of Love, you know? And I was very much politically alig... DAVID CASSIDY Contrary to public opinion and the image people have of me, I grew up in a very lower-middle-class, ... DAVID CASSIDY It was amazing for me growing up in the musical decade of the '60s. I saw The Beatles on televis... DAVID CASSIDY Doing musicals and theatrical productions, I never did any of my hits. DAVID CASSIDY I turned up to all my son's performances and baseball games because my father never did that for... DAVID CASSIDY I was very wary of repeating my father's behaviour and did everything not to act like he did. DAVID CASSIDY Most definitely, my dad was my biggest influence. DAVID CASSIDY My first five albums were triple-platinum, and I played a lot of concerts. DAVID CASSIDY The television and film business has never really been kind or compassionate, in general. DAVID CASSIDY It's amazing what happens to your body as you get a little older. DAVID CASSIDY I didn't end up some sad, tragic guy singing in a lounge somewhere. I never went out and took bi... DAVID CASSIDY Nobody likes to be rejected, you know? DAVID CASSIDY I nearly died twice after I replaced Michael Crawford in 'EFX.' DAVID CASSIDY I work for me, 18 hours a day. It's my gig. So I don't have time to get a point of view. DAVID CASSIDY I don't listen to the news or read newspapers. I don't know what's going on in this worl... DAVID CASSIDY You cannot make a teenage idol. DAVID CASSIDY It's a difficult journey when you're going through a divorce, is it not, for anyone? DAVID CASSIDY Thoroughbred racing is really my true passion. I'm living my dream. DAVID CASSIDY I understand the rock star deal having been one and still going out strapping my guitar on and perfo... DAVID CASSIDY If you put the talent of all my brothers together, they wouldn't add up to the talent that was i... DAVID CASSIDY I'm never going to retire and say, 'This is it. This is my last show.' I will not go on ... DAVID CASSIDY I was silver-white by the time I was 35, but having grey hair makes me look washed out. My wife and ... DAVID CASSIDY I look fine. I've had no surgery apart from an operation I had decades ago to remove the fat und... DAVID CASSIDY I have an audience that goes from kids to seventy year olds. DAVID CASSIDY All my big mistakes are when I try to second-guess or please an audience. My work is always stronger... DAVID BOWIE I read in one fan magazine that I was very self-centered. And I am. DAVID CASSIDY We are too occupied with celebrity. Believe me, it's not what it's cracked to be. DAVID CASSIDY All I had done for five years was work 18 hours a day all over the world. I needed to step back and ... DAVID CASSIDY Everything in my life was about performance when I was doing 'The Partridge Family.' DAVID CASSIDY My mother, Evelyn, was an actress and singer, and my father, Jack, was an actor. My earliest recolle... DAVID CASSIDY Once they began doing 'Celebrity Apprentice,' apparently the audience wasn't that keen o... DAVID CASSIDY My music was never considered cool, but I've always felt that connection with the audience. DAVID CASSIDY I've always had a special relationship with the U.K. fans, because even when I wasn't workin... DAVID CASSIDY My dad left when I was 3 1/2, and he left my mom and I. DAVID CASSIDY I don't play nostalgia acts. I don't play nostalgia shows. DAVID CASSIDY I don't need to remind myself of the trophies. I know what I accomplished. DAVID CASSIDY What I want is credibility I got as a songwriter and actor and doing 'Blood Brothers' on Bro... DAVID CASSIDY In the '80s, it was difficult and frustrating to appear in the theater and TV again, even though... DAVID CASSIDY All that stuff - 'teen idol' - that wasn't me. DAVID CASSIDY I wasn't ever a bad guy, and I was never arrested or anything like that, but I was a wild boy in... DAVID CASSIDY I saw Jimi Hendrix - it must have been four times. And he was incomparable, and his legend lives on. DAVID CASSIDY Acting was absolutely my first focus. I graduated high school in L.A., and two weeks afterwards, I m... DAVID CASSIDY I've really sensed that people have an affection for me. DAVID CASSIDY I've done an enormous amount of bringing light into people's lives, and I'm very proud o... DAVID CASSIDY I bought my first horse when I was 15. I always loved racing and I started studying about breeding a... DAVID CASSIDY I've always had a love for horses since I was really young. When I was 5 years old, the only thi... DAVID CASSIDY My mother gave up a good part of her career to look after me. DAVID CASSIDY In a very short period of time, actors can become kind of relevant and hot. DAVID CASSIDY I played in garage bands and rock and roll bands when I was in junior high and high school and saw s... DAVID CASSIDY I found myself very lost after 'The Partridge Family,' and I lost my dad and I lost my manag... DAVID CASSIDY I've been able to go on and have a successful career on Broadway and certainly the last five yea... DAVID CASSIDY It's not about the fame and the money because if you do good work all that stuff comes. DAVID CASSIDY We live in a world of strange priorities, where Kim Kardashian buying a Lamborghini creates internat... DAVID HAREWOOD The law always limits every power it gives. DAVID HUME There are some four million different kinds of animals and plants in the world. Four million differe... DAVID ATTENBOROUGH Life to me is a journey - you never know what may be your next destination. DAVID RUSSELL False modesty can be worse than arrogance. DAVID MITCHELL This whole world is wild at heart and weird on top. DAVID LYNCH I believe that the war on drugs is a tragically misplaced use of resources - an immoral venture that... DAVID HARSANYI Once you get over the culture shock, Filey is a pleasant spot, particularly at the beginning or end ... DAVID HEWSON Robots have gotten steadily more capable, but humans' expectations that robots should have minds... DAVID HANSON