This study shows that just reducing total fat intake does not go far enough to have an impact on heart disease risk.

I can see how a lot of women might be confused.

I think we should have lowered expectations of what a lifestyle intervention trial can show over a relatively short period of time. Against a climate of less research funding overall, it's going to be harder to do these kinds of trials in the future.

That is a pretty clear signal that there is still something here. I'm hopeful that we will show significant results as we follow these women longer.

I can see how a lot of women might be confused. People would like very clear results with a very clear health message, and, unfortunately, these results are not very clear.

These are secondary analyses and are exploratory to some extent.