It seems that physical activity had an even more pronounced effect among those with the susceptibility gene apoe4, the most important risk factor for Alzheimer's disease and dementia.

It may promote brain plasticity by a direct effect on the brain.

This is the first study to show this long-term relation between physical activity and dementia later in life.

These findings may have wide implications for preventive healthcare. If an individual adopts an active lifestyle in youth, at midlife, this may increase their probability of enjoying both physically and cognitively vital years later in life.

I don't care for physical activity. I'm not sporty. I'm not very coordinated.

I get bursts of creativity with bursts of physical activity.