Women who are at high risk now have a number of options.

Both drugs reduced the risk by approximately 50 percent.

Both drugs lower the risk of developing breast cancer by 50%.

We didn't know if we'd see the benefits in a trial of women at high risk. And in fact, it does hold out.

Over the last few months, I've been telling women who are high risk to stay tuned and we'll wait and see the (study) results before we put them on a preventative treatment.

The specific types of benefits differ in important ways … in women, by reducing the risk of ischemic stroke, and in men, by reducing the risk of heart attack.