With the prefrontal cortex down-regulated, most impulse control mechanisms go offline too. For people who aren't used to this combination, the results can be expensive.

When people say that animal rescuers are crazy, what they really mean is that animal rescuers share a number of fundamental beliefs that makes them easy to marginalize. Among those is the belief that Rene Descartes was a jackass.

When free from the confines of our normal identity, we are able to look at life, and the often repetitive stories we tell about it, with fresh eyes. Come Monday morning, we may still clamber back into the monkey suits of our everyday roles—parent, spouse, employee, boss, neighbor—but, by then, we know they're just costumes with zippers.

Ecstatic technology isn't limited to silicon chips and display screens. As John Lilly's early research established, it's the knowledge of how to tweak the knobs and levers in our brain. When we get it right, it produces those invaluable sensations of selflessness, timelessness, effortlessness, and richness.

When deeply religious subjects view sacred iconography or reflect on their notion of God, brain scans reveal hyperactivity in the caudate nucleus, a part of the pleasure system that correlates with feelings of joy, love, and serenity. But Lindstrom and Calvert found that this same brain region lights up when subjects view images associated with strong brands like Ferrari or Apple.

While we've painted the guardians of the pale in a somewhat reactionary light, let's give the gatekeepers their due. What lies beyond the pale isn't always safe and secure. Outside the fence of state-sanctioned consciousness, there are, to be sure, peaks of profound insight and inspiration. But there are also the swamps of addiction, superstition, and groupthink, where the unprepared can get stuck.