What in hell are you really made of, Howard? After all, it's only a building. It's not the combination of holy sacrament, Indian torture, and sexual ecstasy that you seem to make of it."
"Isn't it?

Thousands of years ago the first man discovered how to make fire. He was probably burnt at the stake he'd taught his brothers to light, but he left them a gift they had not conceived and he lifted darkness from the face of the Earth.

How did you know what's been killing me? Slowly, for years, driving me to hate people when I don't want to hate... Have you felt it, too? Have you seen how your best friends love everything about you--except the things that count? And your most important is nothing to them, nothing, not even a sound they can recognize. You mean, you want to hear? You want to know what I do and why I do it, you want to know what I think? It's not boring to you? It's important?

...Aren’t they all acting on a selfish motive—to be noticed, liked, admired?”
“—by others. At the price of their own self-respect. In the realm of greatest importance—the realm of values, of judgment, of spirit, of thought—they place others above self, in the exact manner which altruism demands. A truly selfish man cannot be affected by the approval of others. He doesn’t need it.

Look,” said Roark evenly, and pointed at the window. “Can you see the campus and the town? Do you see how many men are walking and living down there? Well, I don’t give a damn what any or all of them think about architecture—or about anything else, for that matter. Why should I consider what their grandfathers thought of it?

He’s not really struggling even for material wealth, but for the second-hander’s delusion—prestige. A stamp of approval, not his own. He can find no joy in the struggle and no joy when he has succeeded.