Through the discovery of Buchner, Biology was relieved of another fragment of mysticism. The splitting up of sugar into CO2 and alcohol is no more the effect of a 'vital principle' than the splitting up of cane sugar by invertase. The history of this problem is instructive, as it warns us against considering problems as beyond our reach because they have not yet found their solution.

Discovery consists of looking at the same thing as everyone else and thinking something different.

I told my three sons stories about germs more than fifty years ago as fanciful bedtime tales.

It was quite the most incredible event that has ever happened to me in my life. It was almost as incredible as if you fired a 15-inch shell at a piece of tissue paper and it came back and hit you.

[Recalling in 1936 the discovery of the nucleus in 1909, when some alpha particles were observed instead of travelling through a very thin gold foil were seen to rebound backward, as if striking something much more massive than the particles themselves. He won the Nobel Prize in Chemistry for this discovery.]

Will it be possible to solve these problems? It is certain that nobody has thus far observed the transformation of dead into living matter, and for this reason we cannot form a definite plan for the solution of this problem of transformation. But we see that plants and animals during their growth continually transform dead into living matter, and that the chemical processes in living matter do not differ in principle from those in dead matter. There is, therefore, no reason to predict that abiogenesis is impossible, and I believe that it can only help science if the younger investigators realize that experimental abiogenesis is the goal of biology.