This high degree of organization of prokaryotic [organisms that lack nuclei] genomes is a complete surprise, and this finding carried many implications that biologists might not have considered before. These findings show that evolution of prokaryotes is constrained not just by variations in the content of genes, but also by the intricate ways in which those genes are arranged on chromosomes.

This high degree of organization of prokaryotic genomes is a complete surprise, and this finding carried many implications that biologists might not have considered before. These findings show that evolution of prokaryotes [organisms that lack nuclei] is constrained not just by variations in the content of genes, but also by the intricate ways in which those genes are arranged on chromosomes.

The analysis generated diagrams of psychedelically colored islands of statistically significant patterns floating in a sea of insignificant patterns. Basically, it demonstrated that most bacterial genomes are highly organized. Our results demonstrate that there are significant evolutionary constraints that act upon genomes organization as well as upon genome content. That interplay between organization and function can't be ignored if we want to gain a better fundamental understanding of how a microbial cell works.

There are so few women in general who aren't completely threatened and confused by other women's success. It's very disappointing.

A remembrance can mean nothing to the one remembered; it can only remind the ones left behind how little they did while you were still alive.

To me... San Francisco is an ideal city, intellectually stimulating and naturally beautiful. The oceans and forests are close enough to refresh the spirit; the architecture is always exciting.