This finding that antidepressant use was an independent risk factor for mortality in patients with coronary artery disease was quite unexpected.

they're kind of baby steps. We haven't made any measurable impact on the mortality rate or survival of this disease.

Trash is something you get rid of - or disease. I'm not something you get rid of.

Insurance is so huge. This is labeled a rich girl's disease. All young women are susceptible, but only a few people can afford the treatment that is needed.

We were surprised since antidepressants, particularly the newer class of antidepressants known as selective serotonin reuptake inhibitors (SSRI), have been generally considered safe. However, even after taking into account many patient variables, as well as the type of antidepressant, the risk still remained. So there is something important going on here that we don't fully understand.

Under the right circumstances, for an average or low-risk patient, the mortality risk is very low, ... The risk of complications is very substantial, and the patients need to be prepared.