This appeal isn't designed to be just a sticking plaster. We want to help people across the region to recover and be in a better position when the next crisis hits.

The British public's generosity has helped pull whole regions back from the brink in the past, we now need their help to do that again.

Today's announcement will make a real difference to millions of poor people. On the ground it will mean thousands of people get treatment for the first time in their lives. Zambia will need continued support to recruit new staff but this is a massive leap in the right direction. We now need other African countries to follow suit.

Illegal arms dealers are getting away with murder on a daily basis. Embargoes must be strengthened but even then they will remain a blunt instrument. They are often imposed by the UN Security Council on the basis of politics rather than principles and are usually deployed too late to save lives. The world urgently needs an Arms Trade Treaty if we're to stop weapons getting into the wrong hands .

We need to change the attitudes of people across the world. No matter how small we are, we can make a change.

There is so much more that needs to be done urgently. We need to improve conditions in the spontaneous camps and reach those who have stayed further up in the mountains.