They who are afflicted with it, are seized while they are walking, (more especially if it be up hill, and soon after eating) with a painful and most disagreeable sensation in the breast, which seems as if it would extinguish life, if it were to increase or to continue; but the moment they stand still, all this uneasiness vanishes. . . . In all other respects, patients are, at the beginning of this disorder, perfectly well. . . . Males are most liable to this disease, especially such as have past their fiftieth year.

William Heberden