There's always going to be the circumstances you can't plan for. There's always the unexpected relevance and the serendipity.

If you use it intelligently, Twitter can be a form of engineered serendipity.

I want big ideas to have aesthetic relevance. I want to tickle people's intellectual sensibilities and instill a sense of wonder.

One cannot plan for the unexpected.

I always tell people that revelling in big ideas for me is kind of like an antidote to existential angst.

We're the only species that can look into the future and know that we're going to die one day, and it causes all sorts of cognitive stress on your system.