The way it works is there are certain receptors in the brain that if we block them, can reduce the pleasurable effects associated with drinking.

There is a very real brain component to addiction, and society up to now has for the most part has viewed it as failure of will.

You cannot control your brain activities. It works all the time and it is completely automated process that doesn’t depend on you.

Maybe I can do some writing then. The phrase made him sick. It had no meaning anymore. Like a word that is repeated until it becomes gibberish that sentence, for him, had been used to extinction. It sounded silly; like some bit of cliché from a soap opera. Hero saying in dramatic tones – Now, by God, maybe I can do some writing. Senseless. For a moment, though, he wondered if it was true. Now that she was leaving could he forget about her and really get some work done? Quit his job? Go somewhere and hold up in a cheap furnished room and write? You have $123.89 in the bank, his mind informed him. He pretended it was the only thing that kept him from it. But, far back in his mind, he wondered if he could write anything. Often the question threw itself at him when he was least expecting it. You have four hours every morning, the statement would rise like a menacing wraith. You have time to write many thousands of words. Why don't you? And the answer was always lost in a tangle of becauses and wells and endless reasons that he clung to like a drowning man at straws.(“Mad House”)

I'm sitting in my office trying to squeeze a story from my head. It is that kind of morning when you feel like melting the typewriter into a bar of steel and clubbing yourself to death with it. (“Advance Notice”)

In outward show so splendid and so vain; 'tis but a gilded block without a brain