The size of the effect is remarkable.

The magnitude of this association is quite stunning.

It's comparable to the effects you see for the health benefits that are so often advocated such as exercise [to] keep your blood pressure under control.

If physicians find a drug that's going to drop blood pressure by five [points], they're going to be very happy with that drug.

The take-home message is that feelings of loneliness are a health risk, in that the lonelier you are, the higher your blood pressure. And we know that high blood pressure has all kinds of negative consequences.

I've never known a person to live to be one hundred and be remarkable for anything else