Alison M. Goate quote: "The region of DNA identified in our study showed evidence of replication in four independent series of experiments. I haven't seen a putative risk factor show such consistent results since the e4 variant of the APOE gene was identified as a risk factor for late-onset Alzheimer's disease more than 10 years ago."

Most people have a receptor that's very sensitive to the bitter-tasting compound, but in people that...
ALISON M. GOATE

One particular allele of this polymorphism was being transmitted to alcoholics in these families.
ALISON M. GOATE

We looked in a region of chromosome 7, where there are hundreds of genes, and we noticed that there ...
ALISON M. GOATE

When we understand more about the genes and the environmental factors that influence someone's risk,...
ALISON M. GOATE

In earlier work, we had identified chromosome 7 as a region where there was likely to be a gene-infl...
ALISON M. GOATE

Most people have a receptor that's very sensitive to the bitter-tasting compound, but in people that...
ALISON GOATE

One particular allele of this polymorphism was being transmitted to alcoholics in these families.
ALISON GOATE

We looked in a region of chromosome 7, where there are hundreds of genes, and we noticed that there ...
ALISON GOATE

When we understand more about the genes and the environmental factors that influence someone's risk,...
ALISON GOATE

The region of DNA identified in our study showed evidence of replication in four independent series ...
ALISON GOATE

There are a few genes that have been implicated in the development of early-onset Alzheimer's diseas...
ALISON GOATE

We don't know which of those genes is most likely to harbor this particular risk factor for Alzheime...
ALISON GOATE

In earlier work, we had identified chromosome 7 as a region where there was likely to be a gene-infl...
ALISON GOATE

You know, for most of its life bluegrass has had this stigma of being all straw hats and hay bales a...
ALISON KRAUSS

If you think about it, I was at college, and then three months later, I was a massive pop star. It&#...
ALISON MOYET

Within three months I had gone from being this black sheep of the town to suddenly becoming a pop st...
ALISON MOYET

Samuel Johnson called it the vanity of human wishes, and Buddhists talk about the endless cycle of d...
ALISON GOPNIK

Generally, if a good script comes in I read it, and if it appeals to me, it appeals to me. And it do...
ALISON DOODY

I'd like to take more pictures of real celebrities. It would be fabulous to photograph Brad Pitt...
ALISON JACKSON

Being the boss anywhere is lonely. Being a female boss in a world of mostly men is especially so.
ALISON GOMME

Fly high... Where the only chill that cuts through you is the wind. Where your heart pounds from exh...
VIRGINIA ALISON

The brain is highly structured, but it is also extremely flexible. It's not a blank slate, but i...
ALISON GOPNIK

Where we're located, we're kind of far away from opportunities and activities that might be offered ...
ALISON VINCENT

The other part of the program features things the children haven't been exposed to at home or within...
ALISON VINCENT

With some parents' work schedules, some children might be here at the school for 11 hours.
ALISON VINCENT

The bottom line is that it's for the kids and the parents so they can all have the best experience p...
ALISON VINCENT

Dog cases cause such severe neighbor problems. The dog cases, they get so contentious.
ALISON TATE

Well, I care. If you don't do this, you could die.
ALISON TATE

It's a good thing he didn't touch me. I would have decked him.
ALISON TATE

He's not even close to ready. He is going to lose everything he's gained this far . . . . To show hi...
ALISON TATE

It's hard whenever we lose an animal.
ALISON SWANK

Their counterparts in the wild are out in the weather, too.
ALISON SWANK

We think the overriding cause of her death was something other than drowning.
ALISON SWANK

One of the two suspicions is that there was an indirect lightning strike which may have caused the z...
ALISON SWANK

We're unsure how many are down there.
ALISON SWANK

We do have quite a few people stopping by offering condolences.
ALISON SWANK

The group putting this together was looking for a hurdle that would be doable within the time span, ...
ALISON SMITH

It helps that we know the drugs so we can input it faster.
ALISON SMITH

We saw it as a unique opportunity to use our knowledge to make this run smoothly.
ALISON SMITH

Today, the landscape has changed dramatically.
ALISON SMITH

It sends $3 of your tax money that you already pay into the fund. It sends a message that Maine peop...
ALISON SMITH

We're all going to miss Jack.
ALISON SMITH

In both fours, we viewed the race as an opportunity to work on our race plan against a fast opponent...
ALISON REYNOLDS

There's no evidence to suggest that cooling relations has dampened business.
ALISON REYNOLDS

Many people have used the argument that opening up trade leads to political reform and social reform...
ALISON REYNOLDS

The Tibetan people will not be satisfied until there is political change which will give them genuin...
ALISON REYNOLDS

The police have promised not to do that again and we will demonstrate at every point in this visit.
ALISON REYNOLDS

What we would like to see is Tony Blair making a public statement of concern over these issues.
ALISON REYNOLDS

I'm hearing these words about renewal of the ecumenical movement, but I'm looking for a tangible fra...
ALISON PRESTON

Tracy was frustrated at the start of the season. She wasn't scoring and the links were which wasn't ...
ALISON PRESTON

Annie was frustrated in the preseason but she's steadily improved and has seven goals.
ALISON PRESTON

Everyone was upset when Mackenzie went down. When she came back, their level of play went back up. S...
ALISON PRESTON

Pequannock's only lost two games, both to Madison, so they're obviously a good team.
ALISON PRESTON

When we played Roxbury in the first round, we found out the final would be on our field. It's exciti...
ALISON PRESTON

We've got no superstars but they're getting the job done.
ALISON PRESTON

Kids who commit serious crimes shouldn't go scot-free. But if they are too young to vote or buy ciga...
ALISON PARKER

Frankly, from a human rights perspective, that raises concerns,
ALISON PARKER

We're asking for a recognition that these are child offenders and they should have access to parole ...
ALISON PARKER

For example, Georgia rarely sentences children to life without parole, but it has youth crimes rates...
ALISON PARKER

This would bring us in line with the rest of the world and make the US act in accordance with human-...
ALISON PARKER

[Human rights advocates say that the use of juvenile life without parole, or LWOP, is by one measure...
ALISON PARKER

The big thing was we knew Claudia wasn't going to be able to move that well?[She] really gutted it o...
ALISON OJEDA

We had chance after chance and you only get so many opportunities and we didn't convert.
ALISON OJEDA

As long as we have confidence going into our matches, we have a great shot at winning some of those ...
ALISON OJEDA

Winning sure makes everything more exciting. I thought we played very well. We've been stressing eve...
ALISON OJEDA

As long as these girls have someone to lead them, they will go above and beyond what they are suppos...
ALISON OJEDA

We played in those tournaments to prepare us for the spring, and I think we will be well prepared wh...
ALISON OJEDA

We'll get a lot more eyes on these photos. Our mission was never to keep them in a box.
ALISON NORDSTROM

These are instructions in desire. It's a staged, idealized vision of a perfectly happy household.
ALISON NORDSTROM

I suspect that Rothstein was looking for an opportunity to show the dignity of African Americans, ev...
ALISON NORDSTROM

The Office of War Information asked Parks to provide inspirational photos to support the war effort....
ALISON NORDSTROM

He consciously tried to preserve aspects of old Paris. For example, he didn't shoot the Eiffel Tower...
ALISON NORDSTROM

I was writing and I have three kids. I was occupying my time with them but it was difficult.
ALISON MOYET

I was a single parent, and I was prohibited from working.
ALISON MOYET

I love singing in French. I don't think in French. Sometimes when you sing in another language becau...
ALISON MOYET

I have never had another job and I don't have a mortgage.
ALISON MOYET

I have never done any other job. I have sung in bands since I was 15. I left school completely unqua...
ALISON MOYET

I had been with the label since I was 21. The label wanted shiny pop but I didn't. I found a little ...
ALISON MOYET

I chose not to work. It was one of those sticky things that happen in people's careers when you have...
ALISON MOYET

I came from a small town and at school in one class there was me, a member from Depeche Mode and som...
ALISON MOYET

As you get older, your windows of opportunity close. I needed to make a record once and for all that...
ALISON MOYET

As I was growing up, French was the language in the house, so when I started school there were lots ...
ALISON MOYET

It's always a good thing to have places to go and things to do.
ALISON MORANO

Destinations with a capital D.
ALISON MORANO

The major goal is going to be, they will never say the Democratic Executive Committee wasn't there f...
ALISON MORANO

You'll see more of us in the media. You'll see more of us at events. You'll see more position statem...
ALISON MORANO

This is just the beginning. We are very pleased.
ALISON MARQUISS

We're working on a campaign for the next season and we're also executing on the remediation plan to ...
ALISON MARQUISS

If there were something that were shutting down companies, of course it is vital that our company co...
ALISON MARQUISS

I think with these projections the [Centers for Disease Control and Prevention] will be in a good po...
ALISON MARQUISS

We're approaching the finish line and look forward to providing vaccine for people to get vaccinated...
ALISON MARQUISS

It's an ongoing process.
ALISON MARQUISS

Our third-quarter earnings report is October 25, so we hope to have a more concrete number then, or ...
ALISON MARQUISS

The [FDA] release yesterday was the last regulatory step.
ALISON MARQUISS

[Full FDA clearance has not yet been achieved, but] there are no regulatory hurdles except supplemen...
ALISON MARQUISS

Truth and Consequences
ALISON LURIE

We can lie in the language of dress or try to tell the truth; but unless we are naked and bald, it i...
ALISON LURIE

As one went to Europe to see the living past, so one must visit Southern California to observe the f...
ALISON LURIE

There is a peculiar burning odor in the room, like explosives. the kitchen fills with smoke and the ...
ALISON LURIE

I mean, I like to think of myself as being strong and independent, but I definitely wasn't like that...
ALISON LOHMAN

I mean, God, I'm so lucky right now with the opportunities that I've had. There's nothing to worry a...
ALISON LOHMAN

I like to take a character and develop it.
ALISON LOHMAN

We are all mistaken sometimes; sometimes we do wrong things, things that have bad consequences. But ...
ALISON CROGGON

Being the boss anywhere is lonely. Being a female boss in a world of mostly men is especially so.
ALISON GOMME

It is not given to us to know what difference we can make, and perhaps we can make no difference at ...
ALISON CROGGON

It is only the darkness in our own hearts that will defeat us, in the end.
ALISON CROGGON

There is no shame in not knowing something. The shame is in not being willing to learn.
ALISON CROGGON

While the heart beats, hope lingers.
ALISON CROGGON

Love is one of the true mysteries,' he said at last. 'The truest and the deepest of all. One thing, ...
ALISON CROGGON

My homosexuality remained at that point purely theoretical, an untested hypothesis. But it was a hyp...
ALISON BECHDEL

The writer's business is to find the shape in unruly life and to serve her story. Not, you may note,...
ALISON BECHDEL

My father once nearly came to blows with a female dinner guest about whether a particular patch of e...
ALISON BECHDEL

What would happen if we spoke the truth?
ALISON BECHDEL

In this pause, I suddenly saw something very clearly.

Whatever it was I wanted from my m...
ALISON BECHDEL

It was not a triumphal return. Home, as I had known it, was gone.
ALISON BECHDEL

Grief takes many forms, including the absence of grief.
ALISON BECHDEL

It was a vicious cycle, though. The more gratification we found in our own geniuses, the more isolat...
ALISON BECHDEL

What we want in students is creativity and a willingness to fail. I always say to students, 'If ...
ALISON GOPNIK

I have always loved a hard-faced girl. I get that Alison Goldfrapp isn't easy, and I like her be...
ALISON MOYET

I was always an odd girl; I managed to alienate a lot of people. I felt like a square peg in a round...
ALISON MOYET

I wasn't good at being affable. You get beyond that and realise the attraction in any human bein...
ALISON MOYET

What happens when children reach puberty earlier and adulthood later? The answer is: a good deal of ...
ALISON GOPNIK

I think my cat is adorable, and I probably give it too much fresh chicken. Maybe if I had a child, I...
ALISON GOLDFRAPP

Young children seem to be learning who to share this toy with and figure out how it works, while ado...
ALISON GOPNIK

Spinning has been such an amazing part of my exercise. I love the music, the energy, and the sweat. ...
ALISON SWEENEY

If you're going to saute something, lightly spray olive oil in the pan or on veggies before you ...
ALISON SWEENEY

I'm addicted to a really tough workout. I like to be drenched in sweat when I'm done because...
ALISON SWEENEY

A wedding, people decide to get married, it comes out of such love for one another and then women ca...
ALISON BRIE

The youngest children have a great capacity for empathy and altruism. There's a recent study tha...
ALISON GOPNIK

I recommend that people try new stuff or take new fitness classes all the time. It's important t...
ALISON SWEENEY

Fitness is not an option. It's part of my job.
ALISON SWEENEY

I'll have wine or a piece of cake once in a while, but I don't look at it as sliding backwar...
ALISON SWEENEY

I was definitely one of those people who fell for the fat-free cookies and chips that are loaded wit...
ALISON SWEENEY

When I saw contestants fighting for their lives on 'The Biggest Loser,' I realized I just wa...
ALISON SWEENEY

I eat a lot of fruit after I run. I find that hydrates me better than just drinking water. I have fr...
ALISON SWEENEY

I have two beautiful children and my husband. The perfect day for me is just to be with them and hav...
ALISON SWEENEY

I battled with my weight as a teenager, partly because there wasn't the information or conversat...
ALISON SWEENEY

I've met so many fans of daytime television who've watched the shows with their moms and gra...
ALISON SWEENEY

It's funny because I'm a sucker for glitz and glitter when it comes to clothes and nail poli...
ALISON SWEENEY

The number one mistake is giving pets table scraps. I made the mistake thinking I was showing my dog...
ALISON SWEENEY

I save my dreams and hopes for my kids. When I'm making a wish under a bridge or tunnel, it'...
ALISON SWEENEY

People think, 'Oh, I'm loving myself by sitting on this sofa for four hours.' Love yours...
ALISON SWEENEY

With reality TV, sometimes it's amazing chemistry and you get these gems that turn out to be eve...
ALISON SWEENEY

I wasn't eating the right kinds of calories. I didn't know about healthy carbs such as brown...
ALISON SWEENEY

I always cringe when people tell me they don't eat breakfast, as though that's a good thing....
ALISON SWEENEY

Sunscreen is my number 1, 2, 3, 4, and 5 tip. I'm a fanatic, partially because I live in L.A. an...
ALISON SWEENEY

One of the things I like best about 'Biggest Loser' is being around people who are trying to...
ALISON SWEENEY

My husband and I have known each other since kindergarten. I had a crush on him in school, but we ne...
ALISON SWEENEY

We have lots of evidence that putting investments in early childhood education, even evidence from v...
ALISON GOPNIK

Because Bin Laden's culture doesn't permit the worship of images, they understand how powerf...
ALISON JACKSON

I do a lot of cardio. I think it's super important, especially for women. I don't have a tre...
ALISON SWEENEY

If parents are the fixed stars in the child's universe, the vaguely understood, distant but cons...
ALISON GOPNIK

What makes knowledge automatic is what gets you to Carnegie Hall - practice, practice, practice.
ALISON GOPNIK

I'm not satirical in a traditional way. What I do is more about creating caricatures and cartoon...
ALISON JACKSON

Honestly, my favorite kind of dancing is just lettin' loose. There's something great about t...
ALISON BRIE

I found power in accepting the truth of who I am. It may not be a truth that others can accept, but ...
ALISON GOODMAN

If you just casually look at a baby, it doesn't look like there's very much going on there, ...
ALISON GOPNIK

I just want to act. I just want to do the work.
ALISON LOHMAN

I don't think I'll ever be comfortable with the idea of being famous.
ALISON LOHMAN

I don't know... I don't want people to know everything about me.
ALISON LOHMAN

I did musicals from about age 10 to 18.
ALISON LOHMAN

For Astrid, no matter what challenges they go through, they are going to face each other. It's hard ...
ALISON LOHMAN

But, you know, it really depends on the character. Age doesn't really matter.
ALISON LOHMAN

But you're not necessarily ever going to be handed a script where you can say: it's all done and per...
ALISON LOHMAN

The competition was Coke vs. Pepsi 10 years ago. Our business has evolved over the past 10 years, an...
ALISON LEWIS

So far it [the program] has been great. We have to see how it goes and then gauge its strength. If i...
ALISON LEWIS

The Academy Awards have become much bigger than a night on TV. It has become something we can build ...
ALISON LEWIS

You can never predict ratings. It's more about the association with these marquee entertainment even...
ALISON LEWIS

We didn't think it was ours at halftime. We came back when we played them, and we knew they could do...
ALISON LACEY

I think we didn't play our style of basketball in the second half. I don't know what happened, but y...
ALISON LACEY

I knew Amanda was out (in the first quarter), and I had to take control a bit and just be a good lea...
ALISON LACEY

We definitely don't think about it like we're the favorite; not at all. We know every game is going ...
ALISON LACEY

I think we were a little bit overwhelmed by the atmosphere, but we came back and I'm so proud of the...
ALISON LACEY

She's very efficient; we always know she's going to finish when she gets the ball down low. It's nic...
ALISON LACEY

We were working hard during the (holiday) break, and we came out and we were ready to play. We came ...
ALISON LACEY

If we win state, then we will be No. 1.
ALISON LACEY

We have depth. We know that anybody can come in and play and have good games. Tonight, I thought eve...
ALISON LACEY

Everybody was really welcoming and friendly. They made me feel welcome at all times. I didn't feel u...
ALISON LACEY

On a creative level, I think the songs are simpler in that they're more direct. To be commercially s...
ALISON GOLDFRAPP

Always have sunglasses with you. They're great for when you can't be bothered to put make-up on.
ALISON GOLDFRAPP

We shot it on blue screen, so it was this great big ugly, metal, weird, jerky horse-thing that Brad ...
ALISON GOLDFRAPP

I remember everyone made this big deal out of it,
ALISON GOLDFRAPP

But what's great about working with Will is that I was so bored of working with people who seemed to...
ALISON GOLDFRAPP

They seem to have these personalities that are very generic and so I can't really relate to them. I ...
ALISON GOLDFRAPP

People say that sort of thing and I just think, nah,
ALISON GOLDFRAPP

It's like they're a separate identity to the whole music and imagery,
ALISON GOLDFRAPP

I thought what everyone thinks when they first meet Will,
ALISON GOLDFRAPP

I think I heard it once on Top Of The Pops and thought it was very bland,
ALISON GOLDFRAPP

The take-home message here is that we really need to think about body-image dissatisfaction in boys ...
ALISON FIELD

We found that to be a very strong predictor of starting to use vomiting or laxatives to control weig...
ALISON FIELD

We have known that kids who are overweight or obese have a higher risk for being overweight or obese...
ALISON FIELD

We need to look at the same thing in African American and Hispanic populations.
ALISON FIELD

Parents have to help teens understand that they're comparing themselves to an image that isn't real.
ALISON FIELD

One of the questions we asked them is how much effort they were making to look like females they see...
ALISON FIELD

[The article] was really all about overcoming adversity and pursuing your passion.
ALISON DONLEY

Yoga is actually between 4,000 and 6,000 years old.
ALISON DONLEY

It gives you an opportunity to... recognize when you are letting stress get the best of you. You can...
ALISON DONLEY

You can really practice to your 80's, 90's. It's powerful.
ALISON DONLEY

Alison M. Goate

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