The pain is unrelenting; one does not abandon, even briefly, one's bed of nails, but is attached to it wherever one goes.

In depression . . . faith in deliverance, in ultimate restoration, is absent. The pain is unrelenting, and what makes the condition intolerable is the foreknowledge that no remedy will come -- not in a day, an hour, a month, or a minute. . . . It is hopelessness even more than pain that crushes the soul.

Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self--to the mediating intellect--as to verge close to being beyond description. It thus remains nearly incomprehensible to those who have not experienced it in its extreme mode, although the gloom, "the blues" which people go through occasionally and associate with the general hassle of everyday existence are of such prevalence that they do give many individuals a hint of the illness in its catastrophic form.

it has to be emphasized that if the pain were readily describable most of the countless sufferers from this ancient affliction would have been able to confidently depict for their friends and loved ones (even their physicians) some of the actual dimensions of their torment, and perhaps elicit a comprehension that has been generally lacking; such incomprehension has usually been due not to a failure of sympathy but to the basic inability of healthy people to imagine a form of torment so alien to everyday experience.

I get a fine warm feeling when I'm doing well, but that pleasure is pretty much negated by the pain of getting started each day. Let's face it, writing is hell.

Not to be a-bed after midnight is to be up betimes.