The biggest problem has been exhaustion. I've spent about 6 of the last 14 years completely bedridden.

My biggest problem is retaining the exact information.

The biggest problem was the politicians knew nothing about fighting a war.

The biggest problem with dyslexic kids is not the perceptual problem, it is their perception of themselves. That was my biggest problem.

This is the biggest displacement problem in Africa.

The single biggest problem in communication is the illusion that it has taken place.