Small molecules penetrate the tumor very efficiently, but are also removed very efficiently. Larger molecules penetrate more slowly, but they stay in the tissue longer, giving the patient a greater concentration of the drug. If you balance the two factors with a precise weight, you get optimal drug concentration.
Ashutosh Chilkoti
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GARY F EVANS...
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HENRY JAMES I have prepared myself to be at my peak in London. But in the Olympics, there are so many factors. Y...
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CHRIS HEDGES
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TAMMARA WEBBER
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MARK WELDON We begin to fight. The wind and I. Horns locked. Battling each other with elements.
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Ambos dijeron que tomara asiento y parecían hablar en serio, así que me senté.
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no more pencils, no more books, no more teachers' dirty looks, when the teacher rings the bell, drop...
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If I provide for this life and turn away from the Lord, I am wise for a moment, but lost forever.
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Even longer,' Pooh answered.”
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A.A. MILNE
Love is a growing, or full constant light,
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The more you approach infinity, the deeper you penetrate terror
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STEVE ASMUSSEN I'm not going to get ticked off about winning, but I would have liked to have seen us play with more...
RICHIE MEADE
the room of the spirit is the mind and the seat of the spirit is the heart. What we give room to muc...
ERNEST AGYEMANG YEBOAH
When you live in the present, the past is forgotten & the future takes care of itself.
MANDY HALE
She said 'Over my dead body!' so I took her at her word.
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The end of the world is a strange concept. The world is always ending, and the end is always being a...
NEIL GAIMAN
What is the Other?" they ask.
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PAULO COELHO
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BARUJ BENACERRAF
All day long you sit and sew,
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CHRIS RICHARD If we look at the balance between good and evil, our world as it is has an imbalance of evil and it ...
GARY F EVANS...
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The only perspective is to really be there.
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IN THE MAKING
Financial risk is always associated with drug discovery. But the benefit that a blockbuster drug can...
PANKAJ PATEL
The weight of the world is a trifle, if we all put our two fingers under it and try to lift together...
VERA NAZARIAN
The enlightened one should inspire others by performing all works efficiently without attachment.
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To get over the past, you first have to accept that the past is over. No matter how many times you r...
MANDY HALE His life seemed like a deck of cards, and in the midst of all those two’s and three’s someone ha...
TEKOA MANNING
Now is the only time we have, and the only time that we have any control over.
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She herself is a haunted house. She does not possess herself; her ancestors sometimes come and peer ...
ANGELA CARTER The profound ability to use aural and written language has enabled our species to collectively explo...
KATHERINE VUCICEVIC
No, sweet one. See, my precious: if we has it, then we can escape, even from Him, eh? Perhaps we gro...
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HOWARD GENDELMAN The carriers are realizing to get the last customers they need to offer more than just a mass approa...
MARINA AMOROSO
Very few people possess true artistic ability. It is therefore both unseemly and unproductive to irr...
FRAN LEBOWITZ The novels take longer to write than the picture book texts, and they do take a different sort of co...
MARGARET MAHY
The danger in media concentration comes not from the concentration, but instead from the feudalism t...
LAWRENCE LESSIG