Science is exploration. The fundamental nature of exploration is that we don't know what's there. We can guess and hope and aim to find out certain things, but we have to expect surprises.

Certain things you have to stumble on to. They can't be preprogrammed.

There are certain things in ancient practices that are not worth adhering to.

There are certain things you don't discuss with Ansel, especially if you don't agree.

One of the things my family taught me - I think very important in religion and science - is that you must be ready to stand up for what you think. Decide what you really think is best, and stick with it.

While some of us may know than others about certain things, it is the thinnest slice of all that is, or could be known. In that sense, we are all profoundly ignorant.