Recognizing its importance, Aedes aegypti should be studied as a long-term national, regional, and world problem rather than as a temporary local threat to the communities suffering at any given moment from yellow fever, dengue or other aegypti-borne disease. No one can foresee the extent of the future threat of Aedes aegypti to mankind as a vector of known virus diseases, and none can foretell what other virus diseases may yet affect regions where A. aegypti is permitted to remain.

The use of vaccine in the control of yellow fever should occupy more or less the same place that typhoid fever vaccine has in the control of typhoid fever. No sanitary authority would desire to substitute typhoid vaccine for the supply of pure water and food, so we must not accept the yellow fever vaccine as a substitute for the elimination of Aedes aegypti. The vaccine provides individual protection for the person who cannot be protected by more general measures.

Aedes aegypti, which transmits yellow fever, is one of the feeblest species in its ability for flight and it is at once blown away and destroyed when it gets into a breeze. It therefore seldom wanders from the house in which it was bred.

How to spell Aedes aegypti,the world's one-stop, viral-disease-transmitting mosquito: T-R-O-U-B-L-E.

Will Brazilian antigambiae measures succeed in Africa? As time goes by it will almost certainly be found that an increasing number of areas can be cleaned of gambiae and be freed of gambiae-transmitted malaria. In Africa, where the species is already widely disseminated, it would seem logical to attempt eradication by beginning in the center of the area to be cleaned and working always outward. It has been demonstrated in Brazil that species eradication of Aedes aegypti and Anopheles gambiae is feasible.

Eradicating mosquitoes is a means to an end. An uninfected mosquito is harmless to humans - just a nuisance. An infected mosquito is a danger.