No word is absolutely wrong or dirty or insulting. It all depends upon context and intention.

I have absolutely no intention of marrying Jacqueline Kennedy Onassis.

Not that I recall. I don't use the word juice in that context.

I can't help it. I'm just a big gasbag. I still got leftover barbeque gas." She squeezed her eyes shut tight and did a full minute-long far. "Excuse me," she said.

"There's nothing wrong with being a loser, it just depends on how good you are at it." (as said by Billie Joe)

There's nothing wrong with being a loser,it just depends on how good you are at it