Many nights, I would begin the evening fueled by caffeine and nicotine, which I needed to propel me out of torpor and hopelessness - only to overshoot into quaking, quivering anxiety.

During high school, I would purposely lose tennis and squash matches to escape the agony of anxiety that competitive situations would provoke in me.

There is an element in which anxiety co-represents with aspects of my personality I wouldn't want to give up. It allows you to have foresight. I may not be as empathetic. It's hard to figure out the difference between pathology and personality.

Carly Simon abandoned the stage for seven years after collapsing from nerves before a concert in Pittsburgh in 1981. When she resumed performing, she would sometimes ask members of her band to spank her before she went onstage, to distract her from her anxiety.

The fear of vomiting, which for me is one of the most original and most acute of my fears, is actually fairly common. Emetophobia, it's called, and by some estimates, it's the fifth most common specific phobia.

To say that my anxiety is reducible to the ions in my amygdala is as limiting as saying that my personality or my soul is reducible to the molecules that make up my brain cells or to the genes that underwrote them.