If the Universe possesses intrinsically random elements in their make up, inherited from its quantum origins or from random symmetry-breakings during its early evolution, then we must take our own existence into account when evaluating the correspondence between reality and the cosmological predictions of any Theory of Everything. Moreover, if these random cosmological elements lead to a Universe which differs significantly from place to place over the very large distances, then our local observations of a possibly infinite Universe will inevitably leave our knowledge of its global structure seriously incomplete.

John D. Barrow

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