If a little knowledge is dangerous, where is a man who has so much as to be out of danger?

I am too much of a skeptic to deny the possibility of anything.

From the dawn of exact knowledge to the present day, observation, experiment, and speculation have gone hand in hand; and, whenever science has halted or strayed from the right path, it has been, either because its votaries have been content with mere unverified or unverifiable speculation (and this is the commonest case, because observation and experiment are hard work, while speculation is amusing); or it has been, because the accumulation of details of observation has for a time excluded speculation.

When I reached intellectual maturity, and began to ask myself whether I was an atheist, a theist, or a pantheist; a materialist or an idealist; a Christian or a freethinker, I found that the more I learned and reflected, the less ready was the answer; until at last I came to the conclusion that I had neither art nor part with any of these denominations, except the last. The one thing in which most of these good people were agreed was the one thing in which I differed from them. They were quite sure that they had attained a certain 'gnosis'--had more or less successfully solved the problem of existence; while I was quite sure I had not, and had a pretty strong conviction that the problem was insoluble. And, with Hume and Kant on my side, I could not think myself presumptuous in holding fast by that opinion ...

So I took thought, and invented what I conceived to be the appropriate title of 'agnostic'. It came into my head as suggestively antithetic to the 'gnostic' of Church history, who professed to know so much about the very things of which I was ignorant; and I took the earliest opportunity of parading it at our Society, to show that I, too, had a tail, like the other foxes.

The medieval university looked backwards; it professed to be a storehouse of old knowledge. The modern university looks forward, and is a factory of new knowledge.

It is certain that the labors of these early workers in the field of natural knowledge were brought to a standstill by the decay and disruption of the Roman Empire, the consequent disorganisation of society, and the diversion of men's thoughts from sublunary matters to the problems of the supernatural world suggested by Christian dogma in the Middle Ages. And, notwithstanding sporadic attempts to recall men to the investigation of nature, here and there, it was not until the fifteenth and sixteenth centuries that physical science made a new start, founding itself, at first, altogether upon that which had been done by the Greeks. Indeed, it must be admitted that the men of the Renaissance, though standing on the shoulders of the old philosophers, were a long time before they saw as much as their forerunners had done.