Genes work with probabilities; they don't work with certainties. So most things that you're looking at with these genetic tests, it's not like you're condemned to automatically get the disease or the syndrome. There's a lot of factors in play there.
Sam Kean
Related Are you taking us to the beach?" - Dan Cahill JUDE WATSON It looks ancient," - Amy Cahill JUDE WATSON I can tell you that you will have your hearts broken more by the people you love than by the people ... MARGARET PETERSON HADDIX Let's head out to the ruins." - Dan Cahill ROLAND SMITH It SMELLS ancient," - Dan Cahill JUDE WATSON Palm trees were fanned by a warm, light breeze, and they rolled down their windows to smell the sea. JUDE WATSON But don't get caught out there looking goofy. It's weird. When you do something that stinks,... JAMIE FOXX There is no free lunch, so if you're playing with the big train set - on big movies - it's a... JON FAVREAU In the streets, they're very nice. On Twitter, there are people who love to hate me. Sometimes p... CARICE VAN HOUTEN You love the game, but it's hard to do the things you do when you're feeling like you're... CALVIN JOHNSON Aim high and don't sell yourself short. Know that you're capable. Understand that a lot of p... HOLLY HOLM When you put something out there into the world, there's all these words you don't want to h... JACK WHITE I don't like the whole off-and-on thing. I don't like 'taking a break.' Either you... SELENA GOMEZ It's hard to tell with these Internet startups if they're really interested in building comp... STEVE JOBS With a popular show, you know that there's expectations there, so that's a little nerve-wrac... AARON ASHMORE You're right on the money with that. We're all like detectives in life. There's somethin... DAVID LYNCH I don't watch a whole lot of stand up. Mainly I prefer to read writers; they make me laugh the m... DYLAN MORAN There's many things that you can do with your life. It doesn't necessarily - I think if you&... CATE BLANCHETT You want to work with good people. When you're working with good people, it frees you up. There&... JAMES BADGE DALE When you're doing a TV show, it's not like you just shoot for six weeks and you're in an... CHRIS PRATT It's nice to go and be a guest on a television sitcom. It pays well; it's easy because gener... ISABELLA ROSSELLINI Sometimes there are paparazzi that take photos and you don't know they're there. So you'... DIANNA AGRON You don't have to stick with these recipes. They're guides. As I say, they're a way in. ... SALLY SCHNEIDER I'm still a big 'Grey's Anatomy' fan. BROOKE ELLIOTT I used to watch 'Grey's Anatomy' pretty religiously. ERINN HAYES I just feel like, with rappers, there's so much complacency. It's like, 'Oh, I'm a r... J. COLE I try not to be too optimistic or pessimistic. If you're a pessimist then that's depressing ... NICHOLAS HOULT Baseball players have such a bad rap of, like, 'We don't work out or we're not strong or... BRYCE HARPER Being a funny person does an awful lot of things to you. You feel that you mustn't get serious w... FANNY BRICE You know, the best-laid plans of mice and men... I like playing bad guys, and I don't have a pro... TOBIN BELL It doesn't happen very often that you get to work with some really good friends of yours and the... ELIZABETH PERKINS When I'm not acting, I try to be normal, play golf, play hockey. It's funny because you'... TAYLOR KITSCH Family quarrels are bitter things. They don't go according to any rules. They're not like ac... F. SCOTT FITZGERALD I think it's a very dangerous game to play when you assume that just because someone's an en... WENTWORTH MILLER Television is such an evolving medium. When you're doing a TV show, it's not like you just s... CHRIS PRATT There is a computer disease that anybody who works with computers knows about. It's a very serio... RICHARD P. FEYNMAN When you're a guest star on a movie or a TV show, I always say it's like being invited to a ... ATO ESSANDOH You're allowed to make things for women on television, and there's not like... you don't... CALLIE KHOURI I don't think they're gratuitous with the nudity on 'Game of Thrones.' It's very... NEIL MARSHALL There's a lot of stuff they don't teach you in the mythical editors' school. They don... BILL KELLER People are trying to act like they're balling all day with cars, their house, like there's n... REMY MA It's important to remember that the animals are not grieving with us. They're very accepting... JON KATZ You're allowed to make things for women on television and there's not like... you don't ... CALLIE KHOURI Psychopaths are actually, really, really, really rare in our culture, are people who don't... Or... ANNIE PARISSE Your father tells you a story when you're a kid, or your mother or your uncle or whoever it is. ... DAVID CHASE Whether you like it or not, you're forced to come to the realisation that death is out there. Bu... CLINT EASTWOOD What I believe in and the way I work with my clients is we're so quick to say what we don't ... BRAD GORESKI There's just something about youth and comedy that go together. Maybe it's that foolishness,... JOE FLAHERTY In the film business, when you're young, you just want to work. But when you're older, it ha... ALEC BALDWIN Beside every great success are the seeds of enormous failure. In every failure, there's the oppo... PETER GUBER Be original. That's my best advice. You're going to find that there's something that you... BOB SEGER You're hot for two seconds, and you're struggling to get work again. If it were easy, I don&... TATIANA MASLANY If you're healthy, if you don't get sick much, if you don't go to the doctor much or use... RUSH LIMBAUGH There's a couple of movie parts that I can't remember. There was always something kind of lu... CRAIG ROBINSON I've seen pictures of myself with makeup on, and I look like those women who look like they'... CARRIE FISHER So many times, when you're doing a job, you feel like you're a nuisance at times to people, ... CRAIG SAGER Mathematicians don't like it when they're associated with mental illness and sort of bristle... ETHAN CANIN When taxpayers are subsidizing low wages, people should be aware of that. We're subsidizing an e... NANCY PELOSI In America, you're just an American. You're accepted. It doesn't matter that you're ... BENEDICT WONG There's tremendous shame with being bullied. I think there's a level at which you think that... MATT REEVES That's the beauty of country music - you have to get out there and earn it and work hard. And wh... LUKE BRYAN When you're writing, it's all up to you, and you don't have to make any compromises. And... HENRY SELICK With 'The Vampire Diaries,' it's not just a tease, especially with the relationships. Yo... CANDICE ACCOLA In football, you're dealing with grown men. In gymnastics, you're dealing with prepubescent ... DOMINIQUE MOCEANU No matter who you are, what you've accomplished, what your financial situation is - when you'... MARIA SHRIVER About f-f-ace!" she said to the horse, flailing with her boots. "Into the barn, please. It's time fo... PETER LERANGIS You see?" Damien leaned over his desk and spread out half a dozen charcoal sketches. "These are only... RICK RIORDAN I don't know what makes a writer's voice. It's dozens of things. There are people who wr... PAULA FOX Don't ever, ever, believe anyone who tells you that you can just get by, by doing the easiest th... MARIA BARTIROMO When you're in a play like 'Kean,' you can't think of anything else. Love is too tim... JEAN-PAUL BELMONDO I don't mind close-ups, I like them, but they're kind of forceful - you see a lot, you get a... DAVID DUCHOVNY Sometimes when you're with somebody, and all their stuff is at your house, it's so hard to b... BAM MARGERA The great thing about cake is it doesn't feel like work. You forget about work. Kids, adults, th... DUFF GOLDMAN I'm from the South, and there's a different understanding of how to chop. There's a syll... YELAWOLF A ghost is someone who hasn't made it - in other words, who died, and they don't know they... SYLVIA BROWNE You need to have camaraderie in the clubhouse. Wherever you're working, be it a baseball team or... PAT GILLICK If you've never tasted what it's like to get up in the morning and be pleased to go to work,... LARRY SMITH I'm a little sheepish about it. Whenever I meet fans and they're like, 'Oh, you're s... IDRIS ELBA When you have to work with and exist amongst cynical, burned-out personnel on a set, it doesn't ... HENRY ROLLINS If you don't have a Facebook, like, you're nobody. There's all of these sort of requirem... TAISSA FARMIGA Some people aren't great with babies, or they're not great with a smaller child - it's n... CARA BUONO I love when you get to work with people you know because there's so much more trust, and you'... MALIN AKERMAN I'm not saying standardized tests are the worst ever, but there's an in-between and I don... ASHLEY RICKARDS For me, surfing is as close a connection I can have with Mother Nature. To surf, you're riding a... XAVIER RUDD When you're starting a new business, you don't need to know much about it. A lot of the work... NAVEEN JAIN To be honest, relationships with the opposite sex are the most challenging things I've done. You... DIANE LANE To me, it's just like, if you have talent, and you're lucky enough to find where you fit, an... CAMPBELL SCOTT You're not lonely when you're teaching, you're not quiet, you're laughing most of th... MEM FOX That's part of the curse: If you're gonna play the song, you better play it. I've tried ... EDDIE VEDDER In my normal way of doing things, there's a little bit of 'going native' that takes plac... LOUIS THEROUX When I came out, I found I hadn't been born with the right genes. It's quite brutal. If you&... JOHN GRANT When you're guest-starring, it's very nice, but you're there very briefly, and it's ... ZELJKO IVANEK I don't think comedy is necessarily an attack. It's finding humour in life. I don't thin... DAVID WALLIAMS Here's the point - you're looking at affirmative action, and you're looking at marijuana... JON STEWART You know, I think it's so ironic that we're calling hard work, striving for excellence, don&... AMY CHUA Putting on a movie is like going to war - for me, at least. It's all about time; time is money, ... LEE DANIELS Obviously I've had crushes, and I've tried to make things work with people, but it doesn'... SOPHIE TURNER There are a lot of movies about misfits that are quite cool, that kind of glamorize it on some level... REBECCA HALL There's a lot of work to be done if you're going to run for president or if you're going... MARCO RUBIO The one thing that people don't get about GE is that, to the people who work here, it's not ... JEFFREY R. IMMELT
More Sam Kean
Atoms consist of a positive nucleus and negative electrons flying around outside it. Electrons close... SAM KEAN Most mutations involve typos: Something bumps a cell's elbow as it's copying DNA, and the wr... SAM KEAN I think it's a natural human tendency, when you read something, you tend to read a lot of your p... SAM KEAN Despite what you might guess, when monitoring your breathing, your body doesn't care whether you... SAM KEAN In a vague way, I always knew neurosurgery was different - more delicate, more difficult, more deman... SAM KEAN The grand saga of how humans spread across the globe will need some amendments and annotations - ren... SAM KEAN Scientists didn't discover the noble gas helium - the second most common element in the universe... SAM KEAN Everywhere in the universe, the periodic table has the same basic structure. Even if an alien civili... SAM KEAN Carbon's eastern neighbor on the table, nitrogen, dresses up diamonds in pinks, yellows, oranges... SAM KEAN Guinea pigs are practically synonymous with experiments. Lab rats have become the workhorses of mode... SAM KEAN Medieval alchemists, despite their lust for gold, considered mercury the most potent and poetic subs... SAM KEAN One theme I ran into over and over while writing about the periodic table was the future of energy a... SAM KEAN Despite the disreputable company it keeps, bismuth is harmless. In fact, it's medicinal: Doctors... SAM KEAN The price of diamonds can vary greatly depending on size, cut, color, and other factors, including w... SAM KEAN The body tends to treat elements in the same column of the periodic table as equivalents. SAM KEAN America was probably Europe's equal scientifically by the end of World War I and certainly surpa... SAM KEAN The more that I looked at DNA, the more I realized it was nature and nurture. It's how genes and... SAM KEAN Boron is carbon's neighbor on the periodic table, which means it can do a passable carbon impres... SAM KEAN Most people, even most doctors, learn that the placenta is a nice, tight seal that prevents anything... SAM KEAN I didn't mind staying home from school and medicating myself with vanilla ice cream and chocolat... SAM KEAN Brain surgery couldn't happen without the patient's own active voice to guide the work. The ... SAM KEAN Genes are like the story, and DNA is the language that the story is written in. SAM KEAN On a submicro scale, pure diamond is billions of billions of carbon atoms bonded to one another. If ... SAM KEAN People adored Element 13's color and luster, which reminded them of the sparkle of gold and silv... SAM KEAN While our amplified knowledge of genetics - and the increasing precision of the field - does make it... SAM KEAN The noble gases, which reside on the East Coast of the periodic table, are its aristocrats - detache... SAM KEAN Never underestimate spite as a motivator for genius. SAM KEAN Entrepreneurs in the United States and Europe finally figured out how to separate aluminum from mine... SAM KEAN Some scientists claim - although these claims are contentious - that they can form deadly isomers wi... SAM KEAN Even fictional characters sometimes receive unwarranted medical opinions. Doctors have diagnosed Ebe... SAM KEAN It's often meaningless to talk about a genetic trait without also discussing the environment in ... SAM KEAN In some sense, what you might have suspected from the first day of high-school chemistry is true: Th... SAM KEAN If you had to sum up chemistry in one sentence, it might be this: Atoms need to have full shells of ... SAM KEAN Those of us raised in modern cities tend to notice horizontal and vertical lines more quickly than l... SAM KEAN Aluminum is the most common metal in the earth's crust, almost twice as abundant as iron. And on... SAM KEAN If studying the periodic table taught me nothing else, it's that the credulity of human beings f... SAM KEAN When first presented with the jumble of the periodic table, I scanned for mercury and couldn't f... SAM KEAN The mutated Marfan gene creates a defective version of fibrillin, a protein that provides structural... SAM KEAN Many different elements can form isomers, but only a few elements on the periodic table, like hafniu... SAM KEAN Scientists have continued to tinker with different elements and have learned new ways to store and d... SAM KEAN The most profound change that genetics brings about might not be scientific at all. It might be ment... SAM KEAN Lithium makes a fine battery because it's a scarily reactive metal. Pure lithium ignites on cont... SAM KEAN Geneticists in the early 1900s believed that nature - in an effort to avoid wasting precious space w... SAM KEAN Although it's the hub of the nervous system and the ultimate terminus of every nerve, the brain ... SAM KEAN In 'The Violinist's Thumb,' I talk about the poignancy of cells leaking across the place... SAM KEAN Despite its obscurity, probably no element on the periodic table has as colorful a history as antimo... SAM KEAN Microchimeric sharing means that, even if the mother loses a child, she'll have a small memento ... SAM KEAN Radium, discovered by Marie and Pierre Curie in 1898, was especially popular: the 'it' eleme... SAM KEAN Despite the earnest belief of most of his fans, Einstein did not win his Nobel Prize for the theory ... SAM KEAN Most stars just fuse hydrogen into helium, but larger stars can fuse helium into other elements. Sti... SAM KEAN The amygdala plays a crucial role in processing fear, and minus her two amygdalae, S.M. became unfla... SAM KEAN Atoms of Element 118 fill an outer shell with electrons, creating a special type of element called a... SAM KEAN All human beings are, in fact, born with dozens of mutations their parents lacked, and a few of thos... SAM KEAN Things look especially bleak for common killers such as diabetes and heart disease. Those ailments c... SAM KEAN Mutations can arise anywhere in the genome, in gene DNA and noncoding DNA alike. But mutations to ge... SAM KEAN If certain bacteria, fungi, or algae inch across something made of copper, they absorb copper atoms,... SAM KEAN If stem cells divide equally, so both daughter cells look more or less the same, each one becomes an... SAM KEAN In fact, his travelogues spend amazingly little time discussing his blindness. Only one passage stan... SAM KEAN There are a few elements - especially platinum and palladium - that have the amazing ability to abso... SAM KEAN Unlike uranium, plutonium was created in an American lab in 1940, but scientists soon realized that ... SAM KEAN The idea of critical windows extends beyond just vision, of course: almost every system in the brain... SAM KEAN All we know for sure is that if some astronomer turned a telescope to a far-off star cluster tonight... SAM KEAN Most people who have encountered mercury have done so after breaking a mercury thermometer. And many... SAM KEAN Over the years, humans have managed to incorporate nearly every element, light and weighty, common a... SAM KEAN Even if we never cure a single disease, the Human Genome Project and other ventures will have been w... SAM KEAN As a child in the early 1980s, I tended to talk with things in my mouth - food, dentist's tubes,... SAM KEAN Without a functioning hippocampus, names, dates, and other information falls straight through the mi... SAM KEAN We know that genes shape human cultures and human societies: The DNA we inherited from our ancestors... SAM KEAN Lithium regulates the proteins that control the body’s inner clock. This clock runs, oddly, on DNA... SAM KEAN Animal vision - including human vision - is so biased toward movement that we don't technically ... SAM KEAN Every glass thermometer has subtle variations in the size and shape of the bulb at the bottom and th... SAM KEAN No element gets people telling crazy stories like mercury does. People have told me tales about phar... SAM KEAN Niemożność dostrzeżenia szerszego kontekstu to zwykły skutek uszkodzenia okolic kory przedczoł... SAM KEAN Jupiter instead cooled down below the threshold for fusion, but it maintained enough heat and mass a... SAM KEAN We are safer but we are not yet safe. Four years after 9/11, we are not as safe as we could be. And ... THOMAS KEAN It's not a priority for the government right now. You don't see the Congress or the president talkin... THOMAS KEAN The problem was the CIA and FBI not communicating and not picking them up. THOMAS KEAN Hurricane Katrina pointed out continuing serious flaws in our emergency preparedness and response. A... THOMAS KEAN They're talking about using more money for random checks. Terrorists coming through the airport may ... THOMAS KEAN The first people who reached the World Trade Center did not know who was in charge. Every state and ... THOMAS KEAN There are many things that people think have been done that simply haven't been done. Our leadership... THOMAS KEAN Our purpose is to find out why things happened, how they could have happened, and what we can do to ... THOMAS KEAN We must not allow the people who were struck down to simply become statistics. The greatest service ... THOMAS KEAN It scares me a bit that we dismantled the CIA to the point that it now takes five years to rebuild i... THOMAS KEAN All 10 of us have decided to do everything we can, whether it's testimony or lobbying or speaking or... THOMAS KEAN It shouldn't have happened, it never should have happened. THOMAS KEAN I think this deal is going to be killed. The question is how much damage is this going to do to us b... THOMAS KEAN There's definitely evidence of strange phenomenon in the world. These are well documented, LESLIE KEAN We can't come up with a reason why this information is being withheld. The government won't even ack... LESLIE KEAN We also had a competition between the males and the females for ice cream at lunch. Many of the kids... JUSTIN KEAN What we'll be doing is helping our management [team] manage better by taking the divisions that have... KEAN REGISTER As an interim city manager, you kind of hold the line until a new city manager is hired. The council... KEAN REGISTER My heart only beats for you but you never listen it SAM You want to be happy? you should first learn how to let it go SAM Campaign finance and ethics reform only works if it curtails all special interest groups equally and... THOMAS KEAN, JR. When I face an issue of great import that cleaves both constituents and colleagues, I always take th... THOMAS H. KEAN I always knew that I would give back. My mother and my father both believe you have to work hard and... THOMAS KEAN, JR. We are safer, but we are not yet safe. That's simply not acceptable. THOMAS H. KEAN We owe every student in every neighborhood in New Jersey an equal opportunity to succeed. We know th... THOMAS KEAN, JR. In a cool solitude of trees Where leaves and birds a music spin, Mind that was weary is at... WILLIAM KEAN SEYMOUR Swim upstream. Go the other way. Ignore the conventional wisdom. SAM WALTON Because we're able to adjust for compatibility - and what that means is we've already normal... SAM YAGAN A leader is someone who helps improve the lives of other people or improve the system they live unde... SAM HOUSTON Deep summer is when laziness finds respectability. SAM KEEN We come to love not by finding a perfect person but by learning to see an imperfect person perfectly... SAM KEEN It's a good thing that when God created the rainbow he didn't consult a decorator or he woul... SAM LEVENSON You'll never get mixed up if you simply tell the truth. Then you don't have to remember what... SAM RAYBURN The real actor has a direct line to the collective heart. SAM RAYBURN I like power and I like to use it. SAM RAYBURN Too many critics mistake the deliberations of the Congress for its decisions. SAM RAYBURN If you want to get along, go along. SAM RAYBURN When you get too big a majority, you're immediately in trouble.' SAM RAYBURN Do not wait for extraordinary circumstances to do good action; try to use ordinary situations. SAM RAYBURN Son, always tell the truth. Then you'll never have to remember what you said the last time. SAM RAYBURN You cannot be a leader, and ask other people to follow you, unless you know how to follow, too. SAM RAYBURN I've always been interested in the camera and the effects of it - that's what drew me to fil... SAM RAIMI Any time anyone makes a comic book into a movie, in some way, I think they have to kill the comic bo... SAM RAIMI Some movies to me are like vampires - they suck all of the energy out of me and I don't like tha... SAM RAIMI R is for wussies if you're talking about blood and guts. SAM RAIMI I've always worked with a team of actors and filmmakers ever since I was a kid in Michigan makin... SAM RAIMI I think she said I should seek help. Something like that, but it was in much cruder terms. And that ... SAM RAIMI My father told me to dress to reflect the respect you have for the people around you. I've never... SAM RAIMI I've always heard people's criticisms twice as loudly as their praise. SAM RAIMI Well it's always been an element of the horror film to show us the gross out. I mean that's ... SAM RAIMI It's lovely being a producer. It's really a lot of fun and I can learn a lot. SAM RAIMI As I began making my feature films, it was a great adventure. It was about constructing something I ... SAM RAIMI I feel the horror audience is a great audience, and I would ideally make a movie that would give the... SAM RAIMI I don't like movies about serial killers, necessarily; it's too real and unpleasant for me. SAM RAIMI I don't like shows, I don't like to put on a show, I just really want to work intimately wit... SAM RAIMI I think in every picture that I've ever made. Everything that I've done torments me. I reall... SAM RAIMI I like a good mono track, it's right up front. I don't need all the surrounds telling me the... SAM RAIMI I don't really approach stories to make them different from other stuff I've seen, I just tr... SAM RAIMI I'm not certain, but I have a little gypsy blood in me. And my mother always told me that her gr... SAM RAIMI You know, I put my little brother in the movies and he's still in the pictures. My mother makes ... SAM RAIMI I realized what interested me as a student of film was one thing and the movies that I liked were an... SAM RAIMI Every picture has been a learning opportunity for me. SAM RAIMI That's what heroic stories do for us. They show us the way. They remind us of the good we are ca... SAM RAIMI If a remake is not good, no one wants to see it and, again, it doesn't hurt the original. SAM RAIMI I like something where I can really use my imagination and be an active participant in the construct... SAM RAIMI When we read stories of heroes, we identify with them. We take the journey with them. We see how the... SAM RAIMI I love cats. I've had cats as pets. SAM RAIMI The Price Is Right can really get me going. SAM PECKINPAH Yeah, Dundee was great. It was a great film. I fell in love with my Mexican wife on Dundee. SAM PECKINPAH Why should I give you an interview? All you journalists are plagiarists. SAM PECKINPAH Oh, I find it very easy to fall in love. SAM PECKINPAH The end of a picture is always an end of a life. SAM PECKINPAH Cornwall has lots of folk and Celtic music and has that kind of surfer vibe as well. That was my kin... SAM PALLADIO My family runs a little art gallery back in Cornwall, so flashy cars and things like that have never... SAM PALLADIO As a musician myself, it annoys the hell out of me to watch an actor trying to play a guitar out of ... SAM PALLADIO I am a self-taught guitarist. I just try to piece together passages that have some melodic value! SAM PALLADIO If you break up with a girlfriend or a boyfriend, you're in this vulnerable state where you'... SAM PALLADIO Every actor wants more offers, but I get enough and I do like to be busy. SAM NEILL 'Dexter' I'm very fond of. I got addicted to that. SAM NEILL I can never really remember what I look like. I'm just sort of neutral. I don't think I'... SAM NEILL I'm not big on Champagne, but I'd take along a bottle of Cristal to pop for when the boat co... SAM NEILL I go by the role pretty much. And I think the only genre I haven't gotten to do but I'd love... SAM NEILL As much as possible, I try to encourage people to use stunt men because that is really their job. SAM NEILL When I left university I was working for a documentary film company for six or seven years to the gr... SAM NEILL I understand acting and I understand actors. I don't really understand the world of celebrity. T... SAM NEILL If you want to learn about America, watch 'The Wire.' It's a profound piece of entertain... SAM NEILL I think you need brains to do any Shakespeare with any authority. I could do Shakespeare, but not wi... SAM NEILL When I started in films, it never really occurred to me that I could make a career out of acting. SAM NEILL Try and fit in in a New Zealand playground with an Armagh accent - it doesn't work. SAM NEILL People turn into fools when they see a movie star and do weird things. SAM NEILL I enjoy some physical stuff. But if I had a choice between playing a scene where it's raining, i... SAM NEILL I hate to say it, but there seems to have been some sort of dumbing down as far as movies go. SAM NEILL I've worked all my life to shed myself of any character. SAM NEILL I can tell you where I was when Kennedy was shot - which was in the common room at school. I heard a... SAM NEILL No intelligent man wears a moustache voluntarily - you can write that down. SAM NEILL Actors get pigeonholed very quickly, particularly movie actors. In the theater, one is more used to ... SAM MENDES It's a risk casting anyone against type or what they're known to do. But there's one thi... SAM MENDES For me, certain shots or scenes are keys in the movie. SAM MENDES One of the reasons I loved working with Tom is people feel they know who he is... I think working wi... SAM MENDES I've made movies that cost less than one car chase. SAM MENDES Now I'm back home, living in London, running my theater. I just want to enjoy all that. SAM MENDES Thank God I don't live in Los Angeles. I think if you're there the whole time it just gets o... SAM MENDES I think with Blair Witch and The Sixth Sense, people are much more open to something that is differe... SAM MENDES You think about taking audiences on a journey. SAM MENDES If you lived through the shooting of Jaws, you can live through anything. SAM MENDES I deliberately, in a way, went for something that was a huge challenge and was a big period film. I ... SAM MENDES One movie is only one movie. I want to have a lifetime of making films. SAM MENDES All I know is that I operate by going out to each of them and trying to learn the territory in which... SAM MENDES Shooting action is very, very meticulous, it's increments, tiny little pieces. SAM MENDES The movies that influenced me were movies that told their stories through pictures more than words. SAM MENDES You freeze with the number of opportunities given to you and just decide to do nothing at all. SAM MENDES I want to try and work in different genres with different types of actors, on small movies and big m... SAM MENDES There's good and bad in everybody. I wasn't looking for the good, or looking for the bad. Th... SAM MENDES The characters are trapped within the lifestyle. It's about what goes on before the movie starts... SAM MENDES You've got to work. You've got to want an audience to sit forward in their chairs sometimes,... SAM MENDES I'm certainly getting a lot more mail... that's basically it. SAM MENDES The perceived wisdom is that people do not go in large numbers to black-and-white movies anymore - w... SAM MENDES I don't think good and evil are polarized. SAM MENDES I think movies are a director's medium in the end. Theater is the actor's medium. Theater is... SAM MENDES It took me a long time to film the plastic bag, and then I had to get the cut of the scene right. Bu... SAM MENDES I want to inspire, and be inspired. SAM MENDES Any kid who has two parents who are interested in him and has a houseful of books isn't poor. SAM LEVENSON I admit that: my wife is outspoken, but by whom? SAM LEVENSON Our parents set the moral tone of the family. They expected more of some of us and less of others, b... SAM LEVENSON The difference between keeping things clean and keeping kids clean was that things just sat still an... SAM LEVENSON When I was a boy I used to do what my father wanted. Now I have to do what my boy wants. My problem ... SAM LEVENSON