David (David Foster Wallace) had a caffeine social gift: Her was charmingly, vividly, overwhelmingly awake - he acted on other people like a slug of coffee - so they're the five most sleepless days I every spent with anyone.

This was the first thing I ever said, "All right, I'm gonna try to do the very best I can." Instead of doing this, "All right, I'll work at like three-quarters speed, and then I can always figure that if I just hadn't been a fuckup, the book coulda been really good." You know that defense system? You write the paper the night before, so if it doesn't get a great grade, you know that it could've been better.
And this worked--I worked as hard as I could on this. And in a weird way, you might think that would make me more nervous about whether people would like it. But there was this weird--you know like when you work out really well, there's this kind of tiredness that's real pleasant, and it's sort of placid.

The point of books was to combat loneliness

If you can think of times in your life that you've treated people with extraordinary decency and love, with pure uninterested concern, just because they were valuable as human beings. The ability to do that with ourselves. To treat ourselves the way we would treat a really good, precious friend. Or a tiny child of ours that we absolutely loved more than life itself. And I think it's probably possible to achieve that. I think part of the job we're here for is to learn how to do it. I know that sounds a little pious.

Psychotics, say what you want about them, tend to make the first move.

It's just much easier with dogs. You don't get laid; but you also don't get the feeling you're hurting their feelings all the time.