By definition, big data cannot yield complicated descriptions of causality. Especially in healthcare. Almost all of our diseases occur in the intersections of systems in the body.

I brought one big question with me to Harvard. Why do smart companies fail?

Efficiency innovations provide return on investment in 12-18 months. Empowering innovations take 5-10 years to yield a return. We have ample capital - oceans of capital - that is being reinvested into efficiency innovation.

As a general rule, when a new industry takes root, and the first products emerge in a wave, almost always the architecture of the product will be proprietary and interdependent in character.

Almost always, great new ideas don't emerge from within a single person or function, but at the intersection of functions or people that have never met before.

The single most important factor in our long-term happiness is the relationships we have with our family and close friends.